Description
Canrenone is an active metabolite of spironolactone that acts as an aldosterone antagonist, anti-androgen, and diuretic. Canrenone acts as a partial agonist on the Na+/K+ ATPase.
Canrenone is an active metabolite of spironolactone that acts as an aldosterone antagonist, anti-androgen, and diuretic. Canrenone acts as a partial agonist on the Na+/K+ ATPase.
Cas No. | 976-71-6 |
---|---|
Purity | ≥98% |
Formula | C22H28O3 |
Formula Wt. | 340.46 |
Chemical Name | (17α)-17-Hydroxy-3-oxo-pregna-4,6-diene-21- carboxylic acid γ-lactone |
IUPAC Name | 10,13-dimethylspiro[2,8,9,11,12,14,15, 16-octahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione |
Synonym | Phanurane |
Melting Point | 149-151°C |
Appearance | Light yellow crystal powder |
Store Temp | 4°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Cargnelli G, Trevisi L, Debetto P, et al. Effects of canrenone on aorta and right ventricle of the rat. J Cardiovasc Pharmacol. 2001 May;37(5):540-7. PMID: 11336105.
Corvol P, Claire M, Oblin ME, et al. Mechanism of the antimineralocorticoid effects of spirolactones. Kidney Int. 1981 Jul;20(1):1-6. PMID: 7029118.
Endogenous tachykinin peptide, involved in infl...
D-Seco Paclitaxel is an impurity in the product...
MGMT inhibitor.
Synthetic peptide, retroviral envelope protein ...
FIASMA, μOR agonist, potential HCN channel blo...
Protonophore; chitinase OvCHT1 inhibitor.
PDE and adenosine deaminase inhibitor.
Microtubule polymerization inhibitor, potential...
Steroid; glucocorticoid agonist.
Sesquiterpene lactone derived from Artemesia; m...
Produced by various marine proteobacteria
Minor kavalactone originally found in Piper met...
Endogenous amino acid, also found in meat, dair...
Peptide, used as control to measure RGDS peptid...
Immunostimulator, adjuvant.
Peptide hormone, neurotensin analog found in am...
Monoterpene; nAChR antagonist.
Endogenous peptide fragment, immunostimulant; ...
Endogenous hormone and neurotransmitter involve...
Arp2/3 inhibitor.