Cisplatin is a platinum-based cross-linking agent that exhibits anticancer chemotherapeutic activity. Cisplatin induces crosslinks between guanine bases on DNA; it is clinically used to treat various forms of cancer. In lung cancer cells, cisplatin decreases phosphorylation of PI3K, Akt, and FOXO3a and induces apoptosis. Additionally, cisplatin modulates STAT signaling and immune responses in other models.
| Cas No. | 15663-27-1 |
|---|---|
| Purity | ≥98% |
| Formula | Cl2H6N2Pt |
| Formula Wt. | 300.04 |
| Chemical Name | cis-Dichlorodiammine platinum(II) |
| Synonym | Abiplatin, DDP, Platiblastin, cis- Dichlorodi- ammineplatinum |
| Melting Point | 270°C (dec.) |
| Solubility | Slightly soluble in water. Soluble in DMSO to 60mg/mL. |
| Appearance | Glassy yellow or orange, yellow crystalline powder |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
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