Description
Isosorbide is a diuretic, vasodilator, and antihypertensive that acts as a NO donor. Isosorbide is clinically used to treat hydrocephalus, glaucoma, and angina pectoris.
Product Unit Size | Cost | Quantity | Stock |
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Isosorbide is a diuretic, vasodilator, and antihypertensive that acts as a NO donor. Isosorbide is clinically used to treat hydrocephalus, glaucoma, and angina pectoris.
Cas No. | 16051-77-7 |
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Purity | ≥98% |
Formula | C6H9NO6 |
Formula Wt. | 191.14 |
Chemical Name | 1,4:3,6-Dianhydro-D-glucitol 5-mononitrate |
IUPAC Name | [(3S,3aR,6R,6aS)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate |
Synonym | Isosorbide-5-mononitrate, Corangin, Elantan, Ismo, Monicor, Pentacard |
Melting Point | 88-92°C |
Solubility | Soluble in water, ethanol, methanol, chloroform, ethyl acetate or dicloromethane. |
Appearance | White Crystal Powder |
Store Temp | Ambient |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
Münzel T, Daiber A, Gori T. More answers to the still unresolved question of nitrate tolerance. Eur Heart J. 2013 Sep;34(34):2666-73. PMID: 23864131.
Cohn JN. Efficacy of vasodilators in the treatment of heart failure. J Am Coll Cardiol. 1993 Oct;22(4 Suppl A):135A-138A. PMID: 8376683.
Döring G. Antianginal and anti-ischemic efficacy of nicorandil in comparison with isosorbide-5-mononitrate and isosorbide dinitrate: results from two multicenter, double-blind, randomized studies with stable coronary heart disease patients. J Cardiovasc Pharmacol. 1992;20 Suppl 3:S74-81. PMID: 1282180.
Synthesis impurity
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