Description
JC-1 is a potential-dependent J-aggregate-forming cation that is used to detect changes in the mitochondrial membrane potential.
Product Unit Size | Cost | Quantity | Stock |
---|
JC-1 is a potential-dependent J-aggregate-forming cation that is used to detect changes in the mitochondrial membrane potential.
Cas No. | 3520-43-2 |
---|---|
Purity | ≥90% |
Formula | C25H27Cl4IN4 |
Formula Wt. | 652.23 |
Chemical Name | 5,6-Dichloro-2-[(1E)-3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-propen-1-yl]-1,3-diethyl-1H-3,1-benzimidazol-3-ium iodide |
IUPAC Name | 5,6-Dichloro-2-[(1E)-3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-propen-1-yl]-1,3-diethyl-1H-3,1-benzimidazol-3-ium iodide |
Solubility | Soluble in methanol, DMSO. |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Zhang C, Tian Y, Song F, et al. Salinomycin inhibits the growth of colorectal carcinoma by targeting tumor stem cells. Oncol Rep. 2015 Sep 8. [Epub ahead of print]. PMID: 26352531.
Jiang Z, Li X, Lin Z, et al. Ethyl pyruvate reduces hepatic mitochondrial swelling and dysfunction in a rat model of sepsis. Int J Clin Exp Pathol. 2015 Jul 1;8(7):7774-85. PMID: 26339342.
Smiley ST, Reers M, Mottola-Hartshorn C, et al. Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc Natl Acad Sci U S A. 1991 May 1;88(9):3671-5. PMID: 2023917.
ERK1/2 inhibitor.
Semisynthetic flavone that acts as an inhibitor...
Endogenous peptide, involved in vasoconstrictio...
R-type Ca2+ and voltage-gated Na+ channel block...
JAK2 inhibitor, potential EGFR inhibitor.
HDAC inhibitor.
Imidazole; 14-α demethylase inhibitor.
Imidazole; 14-α demethylase inhibitor.
mAChR antaonist.
ERK1/2 inhibitor.
Vitamin B6 derivative, antioxidant.
NSAID; COX-1/2 inhibitor.
Cathepsin K inhibitor.
Water-soluble coenzyme, vitamin (B7) found in v...
PDE5/6 inhibitor.
Naturally-ocurring neurtral cyclic ionophore, m...
Steviol glycoside used as sucrose substitute
InsR and IGF-1R inhibitor.
Macrolide; vacuolar H+-ATPase inhibitor.
Xanthine derivative; adenosine A2 antagonist, P...