Description
MLN-2238 is a proteasome inhibitor that modulates miR33b, a tumor suppressor microRNA. MLN-2238 exhibits anticancer activity, downregulating Pim-1 activity in multiple myeloma cells.
Product Unit Size | Cost | Quantity | Stock |
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MLN-2238 is a proteasome inhibitor that modulates miR33b, a tumor suppressor microRNA. MLN-2238 exhibits anticancer activity, downregulating Pim-1 activity in multiple myeloma cells.
Cas No. | 1072833-77-2 |
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Purity | ≥95% |
Formula | C14H19BCl2N2O4 |
Formula Wt. | 361.03 |
IUPAC Name | [(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid |
Synonym | Ixazomib |
Solubility | DMSO 72 mg/mL (199.42 mM) Ethanol 9 mg/mL (24.92 mM) Water Insoluble |
Appearance | White Powder |
Store Temp | 4°C |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
Tian Z, Zhao JJ, Tai YT, et al. Investigational agent MLN9708/2238 targets tumor-suppressor miR33b in MM cells. Blood. 2012 Nov 8;120(19):3958-67. PMID: 22983447.
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