Description
PIK-294 is an inhibitor of PI3K that is somewhat selective for p110δ PI3K and less sensitive to p110α PI3K.
Product Unit Size | Cost | Quantity | Stock |
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PIK-294 is an inhibitor of PI3K that is somewhat selective for p110δ PI3K and less sensitive to p110α PI3K.
Cas No. | 900185-02-6 |
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Purity | ≥98% |
Formula | C28H23N7O2 |
Formula Wt. | 489.53 |
IUPAC Name | 2-[[4-amino-3-(3-hydroxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-5-methyl-3-(2-methylphenyl)quinazolin-4-one |
Solubility | DMSO (98 mg/ml), insoluble in water |
Appearance | White to off white powder |
Store Temp | -20°C |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
Hong J, Dicker B, Jayasinghe S, et al. Strong inhibition of neutrophil-sperm interaction in cattle by selective phosphatidylinositol 3-kinase inhibitors. Biol Reprod. 2017 Nov 1;97(5):671-687. PMID: 29036279.
Setti A, Kumar M, Babu K, et al. Potency and pharmacokinetics of broad spectrum and isoform-specific p110gamma and delta inhibitors in cancers. J Recept Signal Transduct Res. 2016;36(1):26-36. PMID: 26791581.
Martin K, Muessel M, Pullar C, et al. The role of phosphoinositide 3-kinases in neutrophil migration in 3D collagen gels. PLoS One. 2015 Feb 6;10(2):e0116250. PMID: 25659107.
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