Ion channel modulators are molecules that influence the action of ion channels. Ion channels are situated in cell membranes, forming pores that allow the passage of ions into and out of cells. This ion trafficking is essential to the biological function of the cell, which includes creating action potentials and other electrical signals, gating the flow of ions, and regulating cell volume.
Manipulation of this flow of ions has interesting effects on both healthy and diseased cells. Ion channel modulators have been used to treat a wide array of conditions from cardiovascular disease to epilepsy to pain and anxiety. Modulators are often categorized by the type of ion they modulate, and can either activate or block the action of the protein. LKT Labs carries a number of ion channel modulators, including those in categories below: