Description
IOX2 is an inhibitor of prolyl hydroxylase that activates HIF-1α and as a result, exhibits pro-angiogenic activity.
IOX2 is an inhibitor of prolyl hydroxylase that activates HIF-1α and as a result, exhibits pro-angiogenic activity.
| Cas No. | 931398-72-0 |
|---|---|
| Purity | ≥98% |
| Formula | C19H16N2O5 |
| Formula Wt. | 352.34 |
| IUPAC Name | 2-[(1-benzyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]acetic acid |
| Solubility | DMSO 7 mg/mL (19.86 mM) DMF 14mg/ml Water Insoluble Ethanol Insoluble |
| Appearance | White Powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Sen A, Ren S, Lerchenmüller C, et al. MicroRNA-138 regulates hypoxia-induced endothelial cell dysfunction by targeting S100A1. PLoS One. 2013 Nov 11;8(11):e78684. PMID: 24244340.
Inhibits NS5A
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ITC, used as chiral agent.
PDE and adenosine deaminase inhibitor.
PDEδ inhibitor.
Dipeptide; aminopeptidase (N/CD13) inhibitor.
Macrolide; protein synthesis inhibitor.
Regioisomers
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Benzisoxazole phenylethanone; D2 and 5-HT2A ant...
Phenylpropene derivative found in essential oil...
PDE5 inhibitor.
Endogenous cardiomodulatory peptide; NPR-A agon...
Anthraquinone found in various plant sources; C...
Downregulates LPS-stimulated expression of pro-...
Synthetic peptide, retroviral envelope protein ...
Endogenous peptide neurotransmitter, involved i...
CB1 agonist, TRPV1 agonist.