LKT Laboratories is pleased to introduce new options for those researchers working with the organosulfur compounds R,S-Sulforaphane and R-Sulforaphane. Both products are now offered at two different purity specifications: ≥99% and ≥97%. Investigators will have the freedom to pick the product that suits their research needs and budgetary constraints.
Sulforaphane is a molecule of significant importance to the scientific community. Since it was first studied in the early 90’s by Talalay, et al. at Johns Hopkins as a major inducer of anticarcinogenic, phase II enzymes, sulforaphane has seen a steady rise in research focus and publications. It has been a part of thousands of major studies, including a record 185 published works in 2016.
LKT Laboratories was the first company to make this compound commercially available in 1995, and continues to be its leading supplier. LKT’s purity standard over the past two decades has always been ≥98%, but with increasing demand for both ultra-pure material and flexibility for researchers, LKT is raising the purity specification on standard product to ≥99% (without increasing its price) as well as introducing the ≥97% version at reduced cost.
The new high purity ≥99% R,S-Sulforaphane and R-Sulforaphane are the purest materials commercially available. They are perfect for long-term projects that may involve animals or other prolonged application periods. Sulforaphane has strict storage requirements to preserve its stability and degrades much more quickly at lower starting purities, which is why LKT recommends the high purity version for projects such as these.
For those looking to use the compound in a shorter time frame, R,S-Sulforaphane and R-Sulforaphane may now be purchased at a ≥97% purity specification at a significantly reduced cost. For research with an immediate application, this product may be a more accessible option.
R,S-Sulforaphane is a synthetic organosulfur compound that displays a variety of interesting characteristics, including anticancer, antimicrobial, antioxidative, anti-inflammatory, and neuroprotective activities. It is a phase II enzyme inducer and induces the expression of the transcription factor Nrf2.
R-Sulforaphane is found naturally in cruciferous vegetables such as broccoli, and has been continuously studied for its health benefits, sometimes showing increased effectiveness compared to its synthetic R,S counterpart in various models.
1. Zhang Y, Talalay P, Cho CG, Posner GH (March 1992). “A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure“. Proc. Natl. Acad. Sci. U.S.A. 89 (6): 2399–2403.