Panaxatriol

Name: Panaxatriol
SKU: P0254
Availability: InStock

Product ID P0254

Cas No. 32791-84-7

Purity ≥98%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Panaxatriol is a triterpene sapogenin originally found in species of Panax (ginseng) that exhibits anti-inflammatory, hepatoprotective, anti-arrhythmic, and antioxidative activities. Panaxatriol increases expression of heme oxygenase 1 (HO-1) and activation of Nrf2 signaling in neurons in a PI3K/Akt-dependent manner. Panaxatriol also decreases acetaminophen-induced increases in ALT and TNF-α, preventing liver injury in vivo. Additionally, panaxatriol inhibits Ca2+ channels, decreasing channel open time and open state probability in vitro and displaying anti-arrhythmic potential.

Product Info

Cas No.	32791-84-7
Purity	≥98%
Formula	C₃₀H₅₂O₄
Formula Wt.	476.73
IUPAC Name	(3S,5R,6R,8R,9R,10R,12R,13R,14R,17S)-4,4,8,10,14-pentamethyl-17-[(2R)-2, 6,6-trimethyloxan-2-yl]-2,3,5,6,7,9,11,12,13,15,16, 17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6,12-triol
Melting Point	238-239C
Solubility	Soluble in DMSO.
Appearance	White Powder

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	P0254 MSDS PDF
Info Sheet	P0254 Info Sheet PDF

References

Huang Y, Yu J, Wan F, et al. Panaxatriol Saponins Attenuated Oxygen-Glucose Deprivation Injury in PC12 Cells via Activation of PI3K/Akt and Nrf2 Signaling Pathway. Oxid Med Cell Longev. 2014;2014:978034. PMID: 24955212.

Wang S, Wang X, Luo F, et al. Panaxatriol saponin ameliorated liver injury by acetaminophen via restoring thioredoxin-1 and pro-caspase-12. Liver Int. 2013 Sep 11. [Epub ahead of print]. PMID: 24119161.

Zhang WJ, Zhong GG, Jiang Y, et al. Single channel analysis on calcium channel blockade action of panaxadiol and panaxatriol saponins on cultured rat ventricular myocytes. Zhongguo Yao Li Xue Bao. 1994 Mar;15(2):173-6. PMID: 7516611.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Email
This field is for validation purposes and should be left unchanged.

Panaxatriol

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Bradykinin (1-7)

Afatinib

Paeonol

Bupivacaine Hydrochloride Monohydrate

XAV-939

Methyldopa Sesquihydrate

Bambuterol Hydrochloride

Icariin

Sotorasib racemate

Carbinoxamine Maleate

Glucosamine Sulfate Potassium Chloride

D-Luciferin 1-(4,5-dimethoxy-2-nitrophenyl) Ethyl Ester

Swainsonine

Phenethyl Dimethyl Caffeate

Diaveridine

Pituitary Adenylate Cyclase-activating Peptide (6-38), human/sheep/rat

S-Sulforaphane

Corynoline

M40

Rosmarinic Acid

Footer