LKT Labs

Biochemicals for Life Science Research

Cyclophosphamide Monohydrate

Cyclophosphamide Monohydrate

Product ID C9609
Cas No. 6055-19-2
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $71.00 In stock
5 g $210.00 In stock
Bulk Quote

Quicklinks

Description

Cyclophosphamide is a nitrogen mustard that acts as an alkylator, adding alkyl groups to the N7 nitrogen of guanine bases; this inhibits DNA repair and replication. Cyclophosphamide exhibits anticancer chemotherapeutic and immunomodulatory activities. This compound is one component in the CHOP chemotherapy regimen. Cyclophosphamide is clinically used to treat various cancers, graft-versus-host disease (GvHD), and autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and systemic lupus erythematous (SLE).

Product Info

Cas No.

6055-19-2
Purity

≥98%
Formula

C7H15Cl2N2O2P • H2O
Formula Wt.

279.10
Chemical Name

N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-ox- azaphosphorin-2-amine 2 oxide monohydrate
IUPAC Name

N,N-bis(2-chloroethyl)-2-oxo-1,3,2λ5-oxazaphosphinan-2-amine;hydrate
Synonym

Cycloblastin, Cyclostin, Cytoxan, Endoxan

Melting Point

41-45°C
Solubility

Soluble in water. Slightly soluble in ethanol.
Appearance

White crystalline powder

Shipping and Storage

Store Temp

4°C
Ship Temp

Ambient

Downloads

MSDS

C9609 MSDS PDF
Info Sheet

C9609 Info Sheet PDF

References

Sistigu A, Viaud S, Chaput N, et al. Immunomodulatory effects of cyclophosphamide and implementations for vaccine design. Semin Immunopathol. 2011 Jul;33(4):369-83. PMID: 21611872.

Makhani N, Gorman MP, Branson HM, et al. Cyclophosphamide therapy in pediatric multiple sclerosis. Neurology. 2009 Jun 16;72(24):2076-82. PMID: 19439723.

Hall AG, Tilby MJ. Mechanisms of action of, and modes of resistance to, alkylating agents used in the treatment of haematological malignancies. Blood Rev. 1992 Sep;6(3):163-73. PMID: 1422285.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • S0133

    Saikosaponin C

    Triterpene saponin found in Bupleurum.

    ≥98%
  • V3276

    Vitamin E, Natural

    Antioxidant.

    ≥97%
  • L3374

    Lisinopril Dihydrate

    Enalapril analog; ACE inhibitor.

    ≥98%
  • N0114

    Nadifloxacin

    Fluoroquinolone; bacterial DNA gyrase inhibitor...

    ≥98%
  • D5662

    Dopamine Hydrochloride

    Endogenous hormone neurotransmitter, involved i...

    ≥99%
  • A4935

    6-Aminocaproic Acid

    Protease inhibitor.

    ≥98%
  • D0010

    3H-1,2-Dithiole-3-thione

    Induces activation of Nrf2; inhibits apoptosis ...

    ≥98%
  • G720004

    GS-4997

    ASK1 inhibitor.

    ≥99%
  • T1952

    Tenuazonic Acid Copper Salt

    Mycotoxin produced by Alternaria; photosynthesi...

    ≥98%
  • A985130

    AZD-7762

    CHK1 inhibitor.

    ≥98%
  • D5992

    Doxapram Hydrochloride Hydrate

    K+ channel blocker, catecholamine release stimu...

    ≥98%
  • E6397

    EPZ6438

    Potent and selective inhibitor

    ≥98%
  • A0910

    N-Acetyl-S-(N′-phenylthiocarbamoyl)-L-cysteine

    Cysteine-ITC conjugate, antioxidant.

    ≥98%
  • M9710

    Mycophenolic Acid

    Phthalide; PPARγ agonist, IMPDH inhibitor, mic...

    ≥98%
  • B5648

    Bombesin

    GRP analog, found in Bombina; bombesin and GRP ...

    ≥95%
  • V1868

    Veratramine

    Steroidal alkaloid found in Veratrum and Fritil...

    ≥98%
  • G4662

    GLPG-0634

    JAK1 inhibitor.

    ≥98%
  • E5576

    Entecavir

    Nucleoside (deoxyguanosine) analog; DNA chain t...

    ≥97%
  • W7200

    WS3

    Islet β cell proliferation stimulator.

    ≥98%
  • D4802

    17-Dimethylaminoethylamino Demethoxygeldanamycin

    Geldanamycin derivative; HSP90 inhibitor.

    ≥98%