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Ramelteon

Product ID R0348
Cas No. 196597-26-9
Purity ≥99%
Product Unit SizeCostQuantityStock
10 mg $177.90 In stock
25 mg $342.60 In stock
100 mg $1,026.80 In stock
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  • Description
  • Product Info
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  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ramelteon is a melatonin MT1/2 receptor agonist used clinically to treat insomnia. Ramelteon displays hypnotic activity and may be immunostimulatory as well. In animal models, ramelteon decreases wakefulness and increases slow-wave and rapid eye movement (REM) sleep.

Product Info

Cas No.

196597-26-9

Purity

≥99%

Formula

C16H21NO2

Formula Wt.

259.34

Chemical Name

(S)-N-[2-(1,6,7,8-tetrahydro-2H-indeno-[5,4-b] furan-8-yl)ethyl]propionamide

IUPAC Name

N-[2-[(8S)-2,6,7, 8-tetrahydro-1H-cyclopenta[e][1]benzofuran-8-yl]ethyl]propanamide

Melting Point

113-116°C

Solubility

Soluble in water (<1.2 mg/ml), ethanol (≥50 mg/ml), DMSO (≥50 mg/ml), DMF, and methanol

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

R0348 MSDS PDF

Info Sheet

R0348 Info Sheet PDF

References

Fourman LT, Robert Meyer B. Autoimmune hepatitis in association with ramelteon. J Clin Gastroenterol. 2013 Aug;47(7):651-4. PMID: 23632362.

Zammit GK. Ramelteon: a novel hypnotic indicated for the treatment of insomnia. Psychiatry (Edgmont). 2007 Sep;4(9):36-42. PMID: 20532119.

Miyamoto M, Nishikawa H, Doken Y, et al. The sleep-promoting action of ramelteon (TAK-375) in freely moving cats. Sleep. 2004 Nov 1;27(7):1319-25. PMID: 15586784.

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