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Aminophylline Anhydrous

Aminophylline Anhydrous

Product ID A5134
Cas No. 317-34-0
Purity ≥98%
Product Unit SizeCostQuantityStock
25 g $81.70 In stock
100 g $132.60 In stock
500 g $408.30 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Aminophylline is a non-selective adenosine receptor antagonist and phosphodiesterase (PDE) inhibitor. Aminophylline exhibits vasodilatory and anti-inflammatory activity and is occasionally clinically used to treat chronic obstructive pulmonary disorder (COPD). In animal models of allergen-induced lung inflammation, aminophylline decreases levels of IL-5, IL-8, and eosinophils.

Product Info

Cas No.

317-34-0

Purity

≥98%

Formula

C16H24N10O4

Formula Wt.

420.43

Chemical Name

3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione compd with 1,2-ethanediamine (2:1)

IUPAC Name

1,3-dimethyl-7H-purine-2,6-dione;ethane-1,2-diamine

Synonym

Aminophylline, Afonilum, Cardophylin, Pecram, Phyllotemp, Tefamin

Melting Point

269-270°C

Solubility

Soluble in water. Insoluble in alcohol and ether.

Appearance

A white or slightly yellowish powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

A5134 MSDS PDF

Info Sheet

A5134 Info Sheet PDF

References

Nickels TJ, Schwartz AD, Blevins DE, et al. Effect of theophylline and aminophylline on transmitter release at the mammalian neuromuscular junction is not mediated by cAMP. Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):465-70. PMID: 16700879.

Danahay H, Broadley KJ, McCabe PJ, et al. The potential roles of cytokines, IL-5 and IL-8, and plasma cortisol in the anti-inflammatory actions of phosphodiesterase inhibitors in sensitized guinea-pig airways. Pulm Pharmacol Ther. 1997 Oct-Dec;10(5-6):277-85. PMID: 9778491.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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