• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
AT-7519 Hydrochloride

AT-7519 Hydrochloride

Product ID A761003
Cas No. 902135-91-5
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $99.80 In stock
25 mg $341.30 In stock
100 mg $682.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

AT-7519 is an ATP competitive CDK inhibitor showing activity against CDK1, 2, 4, 6, and 9. It causes cell cycle arrest followed by apoptosis in human tumor cells and inhibits tumor growth in human tumor xenograft models. It also induces apoptosis in multiple myeloma cells via GSK-3β activation.

Product Info

Cas No.

902135-91-5

Purity

≥98%

Formula

C16H17Cl2N5O2 • HCl

Formula Wt.

418.70

Chemical Name

n-(4-Piperidinyl)-4-(2,6-dichlorobenzoylamino)-1h-pyrazole-3-carboxamide hydrochloride

IUPAC Name

4-[(2,6-Dichlorobenzoyl)amino]-N-(4-piperidinyl)-1H-pyrazole-3-carboxamide hydrochloride (1:1)

Synonym

AT 7519 HCl; 4-(2,6-dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide hydrochloride

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A761003 MSDS PDF

Info Sheet

A761003 Info Sheet PDF

References

Santo L., Vallet S., et al. AT7519, A novel small molecule multi-cyclin-dependent kinase inhibitor, induces apoptosis in multiple myeloma via GSK-3β activation and RNA polymerase II inhibition. Oncogene. 29:2325-2336 (2010). PMID: 20101221.

Squires M., Feltell R., et al. Biological characterization of AT7519, a small-molecule inhibitor of cyclin-dependent kinases, in human tumor cell lines. Molecular Cancer Therapeutics. 8(2):324-332 (2009). PMID: 19174555.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • Z161022

    α-Zearalanol

    Mycotoxin that has structural similarity to est...

    ≥98%
  • M9367

    Myricetin

    Flavonol found in fruits and vegetables; COMT i...

    ≥98%
  • G4597

    18β-Glycyrrhetinic Acid

    Triterpene glycoside found in Glycyrrhiza; 15-H...

    ≥98%
  • P2000

    PF-03758309 Dihydrochloride

    PAK4 inhibitor.

    ≥99%, ≥99%ee
  • C2802

    CH5132799

    p110α PI3K inhibitor.

    ≥98%
  • A7658

    Atorvastatin Calcium Trihydrate

    Statin; HMG-CoA reductase inhibitor.

    ≥98%
  • D5611

    Docosahexaenoic Acid (all cis-4,7,10,13,16,19) Methyl Ester

    Essential fatty acid found in fish oil, involve...

    ≥99%
  • A4498

    Alytesin

    Antimicrobial peptide found in amphibians.

    ≥95%
  • P1869

    Perindopril Erbumine

    ACE inhibitor.

    ≥95%
  • S1604

    Secretin Acetate

    Endogenous peptide hormone, involved in feeding...

    ≥95%
  • A4523

    Alfuzosin Hydrochloride

    α1-adrenergic antagonist.

    ≥97%
  • T0004

    T2 toxin Triol

    Trichothecene mycotoxin produced by Fusarium; p...

    ≥97%, TLC
  • U0618

    Ubenimex

    Dipeptide; aminopeptidase (N/CD13) inhibitor.

    ≥98%
  • Z0252

    Zanamivir

    Neuraminidase inhibitor.

    ≥98%
  • T1008

    10,13-Bissidechain Paclitaxel

    Synthesis impurity

    ≥90%
  • M1976

    Methimazole

    Thioamide; thyroid peroxidase inhibitor.

    ≥98%
  • H1893

    Hexarelin

    Synthetic ghrelin analog; ghrelin agonist.

    ≥95%
  • A6804

    Arbutin

    Glycoside hydroquinone originally found in Berg...

    ≥98%
  • D023721

    Dasatinib

    Multikinase inhibitor.

    ≥99%
  • R2815

    Recombinant HIV-1 “0” group consensus

    Recombinant HIV-1 antigen fragment.

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only