Description
Caerulomycin A is a bipyridyl antifungal antibiotic. Caerulomycin A is toxic to Entamoeba in animal models of infection. Additionally, caerulomycin may exhibit anticancer and immunosuppressive activities.
| Product Unit Size | Cost | Quantity | Stock |
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Caerulomycin A is a bipyridyl antifungal antibiotic. Caerulomycin A is toxic to Entamoeba in animal models of infection. Additionally, caerulomycin may exhibit anticancer and immunosuppressive activities.
| Cas No. | 21802-37-9 |
|---|---|
| Purity | ≥96% |
| Formula | C12H11N3O2 |
| Formula Wt. | 229.23 |
| Chemical Name | (2Z)-4-methoxy-2-(nitrosomethylidene)-6-pyridin-2-yl-1H-pyridine |
| IUPAC Name | (2Z)-4-methoxy-2-(nitrosomethylidene)-6-pyridin-2-yl-1H-pyridine |
| Synonym | Cerulomycin |
| Appearance | White powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Tong L, Sun W, Wu S, et al. Characterization of caerulomycin A as a dual-targeting anticancer agent. Eur J Pharmacol. 2022 May 5:922:174914. PMID: 35337812.
Zhu Y, Zhang Q, Li S, et al. Insights into Caerulomycin A Biosynthesis: A Two-Component Monooxygenase CrmH-Catalyzed Oxime Formation. J Am Chem Soc. 2013 Dec 5. [Epub ahead of print]. PMID: 24295370.
Cristalli G, Franchetti P, Grifantini M, et al. 2,2'-Bipyridyl-6-carboxamidoximes with potential antitumor and antimicrobial properties. Farmaco Sci. 1986 Jul;41(7):499-507. PMID: 3743743
Chatterjee DK, Raether W, Iyer N, et al. Caerulomycin, an antifungal antibiotic with marked in vitro and in vivo activity against Entamoeba histolytica. Z Parasitenkd. 1984;70(5):569-73. PMID: 6095553.
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