Description
Chlorzoxazone is a centrally acting muscle relaxant, causing central nervous system depression. It also acts as a positive SK-type potassium channel modulator. This activity reduces alcohol intake in rats, with no effect on water intake.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Chlorzoxazone is a centrally acting muscle relaxant, causing central nervous system depression. It also acts as a positive SK-type potassium channel modulator. This activity reduces alcohol intake in rats, with no effect on water intake.
| Cas No. | 95-25-0 |
|---|---|
| Purity | ≥99% |
| Formula | C7H4ClNO2 |
| Formula Wt. | 169.56 |
| Chemical Name | 5-Chloro-2-benzoxazolone |
| IUPAC Name | 5-chloro-3H-1,3-benzoxazol-2-one |
| Synonym | Chlorzoxazon, Paraflex, Chloroxazone, 5-Chloro-2-benzoxazolone |
| Melting Point | 189-192°C |
| Solubility | Very slightly soluble in water. Soluble in DMSO - 50 mg/mL. |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Hopf F., Simms J., et al. Chlorzoxazone, an SK-type potassium channel activator used in humans, reduces excessive alcohol intake in rats. Biol Psychiatry. 69(7):618-24 (2011). PMID: 21195386.
FIASMA, SERT inhibitor, 5-HT and σ1 antagonist...
H1 histamine and LT antagonist, PDE inhibitor.<...
Endogenous neuropeptide hormone, involved in so...
D2/3 antagonist, hERG K+ channel blocker.
Synthetic non-digestible disaccharide.
Selective HDAC4 and HDAC5 inhibitor.
Indole alkaloid found in Evodia rutaecarpa; top...
BH3 mimetic; Bcl-2 and Bcl-xl inhibitor.
Cyclic depsipeptide is a secondary metabolite i...
Synthesis impurity
Melatonin analog; MT1/2 agonist, 5-HT2C antagon...
Macrocyclic lactone.
AurK, FLT3, Abl inhibitor.
ROCK inhibitor.
TRPA1 antagonist
Alkylphospholipid analog; Akt inhibitor.
Fluoroquinolone; bacterial DNA gyrase inhibitor...
Tricyclic benzonaphthyridinone; mTORC1/2 inhibi...
Aspirin analog; hemoglobin chain cross-linker.<...
Polyphenol derivative of caffeic acid found in ...