Description
Chlorzoxazone is a centrally acting muscle relaxant, causing central nervous system depression. It also acts as a positive SK-type potassium channel modulator. This activity reduces alcohol intake in rats, with no effect on water intake.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Chlorzoxazone is a centrally acting muscle relaxant, causing central nervous system depression. It also acts as a positive SK-type potassium channel modulator. This activity reduces alcohol intake in rats, with no effect on water intake.
| Cas No. | 95-25-0 |
|---|---|
| Purity | ≥99% |
| Formula | C7H4ClNO2 |
| Formula Wt. | 169.56 |
| Chemical Name | 5-Chloro-2-benzoxazolone |
| IUPAC Name | 5-chloro-3H-1,3-benzoxazol-2-one |
| Synonym | Chlorzoxazon, Paraflex, Chloroxazone, 5-Chloro-2-benzoxazolone |
| Melting Point | 189-192°C |
| Solubility | Very slightly soluble in water. Soluble in DMSO - 50 mg/mL. |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Hopf F., Simms J., et al. Chlorzoxazone, an SK-type potassium channel activator used in humans, reduces excessive alcohol intake in rats. Biol Psychiatry. 69(7):618-24 (2011). PMID: 21195386.
Avermectin; glu-gated Cl- channel activator, Gl...
Phenylpyrazoleanilide; IL-17 production inhibit...
Antimicrobial peptide found in Apis mellifera.<...
Synthetic peptide derived from HIV-1; viral fus...
Triterpene saponin found in species of Panax; Î...
Diterpene found in brewed, unfiltered coffee; F...
Anthraquinone found in various plant sources.
Endogenous peptide, involved in stress signalin...
Snake venom found in Bothrops alternatus urutu....
CHK1 inhibitor.
Glycylcycline; protein synthesis inhibitor.
Diterpene found in coffee beans.
Adenosine A2A antagonist.
Indole alkaloid found in Evodia rutaecarpa; top...
Isoflavone, phytoestrogen found in soy
M4 mAChR agonist, 5-HT1A partial agonist, M1/2/...
Islet α/β cell proliferation stimulator.
Alkaloid found in Galanthus, Narcissus, Leucoju...
Cyclic peptide; calcineurin inhibitor.
NSAID; COX-1/2 inhibitor.