Description
Chlorzoxazone is a centrally acting muscle relaxant, causing central nervous system depression. It also acts as a positive SK-type potassium channel modulator. This activity reduces alcohol intake in rats, with no effect on water intake.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Chlorzoxazone is a centrally acting muscle relaxant, causing central nervous system depression. It also acts as a positive SK-type potassium channel modulator. This activity reduces alcohol intake in rats, with no effect on water intake.
| Cas No. | 95-25-0 |
|---|---|
| Purity | ≥99% |
| Formula | C7H4ClNO2 |
| Formula Wt. | 169.56 |
| Chemical Name | 5-Chloro-2-benzoxazolone |
| IUPAC Name | 5-chloro-3H-1,3-benzoxazol-2-one |
| Synonym | Chlorzoxazon, Paraflex, Chloroxazone, 5-Chloro-2-benzoxazolone |
| Melting Point | 189-192°C |
| Solubility | Very slightly soluble in water. Soluble in DMSO - 50 mg/mL. |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Hopf F., Simms J., et al. Chlorzoxazone, an SK-type potassium channel activator used in humans, reduces excessive alcohol intake in rats. Biol Psychiatry. 69(7):618-24 (2011). PMID: 21195386.
Prolyl hydroxylase inhibitor.
Non-alkaloid lignan found in Podophyllum,deriva...
Diterpene found in brewed, unfiltered coffee; F...
HDM2 inhibitor
Antimicrobial peptide found in bee and wasp ven...
Glycosaminoglycan
Thiazide diuretic; NCCT inhibitor, carbonic anh...
Vitamin E component
Acyclic nucleotide (adenosine) analog; viral DN...
Cyclosporin metabolite; weak calmodulin inhibit...
Endogenous peptide hormone, involved in stress ...
ITC, radical scavenger.
Endogenous tachykinin peptide, involved in infl...
Semi-synthetic peptide, melanocortin analog; MC...
Endogenous peptide hormone inolved in gastric e...
β-lactam carbapenem; penicillin binding protei...
HSP90 inhibitor.
ACE inhibitor.
Endogenous peptide, involved in paracrine and a...
Carbonic anhydrase inhibitor.