Description
Chlorzoxazone is a centrally acting muscle relaxant, causing central nervous system depression. It also acts as a positive SK-type potassium channel modulator. This activity reduces alcohol intake in rats, with no effect on water intake.
| Product Unit Size | Cost | Quantity | Stock |
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Chlorzoxazone is a centrally acting muscle relaxant, causing central nervous system depression. It also acts as a positive SK-type potassium channel modulator. This activity reduces alcohol intake in rats, with no effect on water intake.
| Cas No. | 95-25-0 |
|---|---|
| Purity | ≥99% |
| Formula | C7H4ClNO2 |
| Formula Wt. | 169.56 |
| Chemical Name | 5-Chloro-2-benzoxazolone |
| IUPAC Name | 5-chloro-3H-1,3-benzoxazol-2-one |
| Synonym | Chlorzoxazon, Paraflex, Chloroxazone, 5-Chloro-2-benzoxazolone |
| Melting Point | 189-192°C |
| Solubility | Very slightly soluble in water. Soluble in DMSO - 50 mg/mL. |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Hopf F., Simms J., et al. Chlorzoxazone, an SK-type potassium channel activator used in humans, reduces excessive alcohol intake in rats. Biol Psychiatry. 69(7):618-24 (2011). PMID: 21195386.
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