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Procarbazine Hydrochloride

Product ID P6858
Cas No. 366-70-1
Purity ≥97%
Product Unit SizeCostQuantityStock
100 mg $92.50 In stock
500 mg $240.70 In stock
1 g $370.40 In stock
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Procarbazine is a hydrazine derivative that exhibits anticancer chemotherapeutic activity. Procarbazine acts as a DNA alkylator and induces double stranded DNA breaks and causes oxidative damage. Clinically, procarbazine is used to treat Hodgkin’s lymphoma and brain cancers. This compound also inhibits monoamine oxidase (MAO).

Product Info

Cas No.

366-70-1

Purity

≥97%

Formula

C12H19N3O • HCl

Formula Wt.

257.76

Chemical Name

N-(1-Methylethyl)-4-[(2- methylhydrazino)methyl]- benzamide hydrochloride

IUPAC Name

4-[(2-methylhydrazinyl)methyl]-N-propan-2-ylbenzamide;hydrochloride

Synonym

Matulane, Natulan

Melting Point

223-226°C

Solubility

Soluble in water.

Appearance

White crystalline powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

P6858 MSDS PDF

Info Sheet

P6858 Info Sheet PDF

References

Ogawa K, Hiraku Y, Oikawa S, et al. Molecular mechanisms of DNA damage induced by procarbazine in the presence of Cu(II). Mutat Res. 2003 Aug 5;539(1-2):145-55. PMID: 12948823.

Kyrtopoulos SA, Anderson LM, Chhabra SK, et al. DNA adducts and the mechanism of carcinogenesis and cytotoxicity of methylating agents of environmental and clinical significance. Cancer Detect Prev. 1997;21(5):391-405. PMID: 9307842.

Custom Order

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