Description
E64 is an inhibitor of cysteine proteases. E64 decreases production of IL-8 in vitro.
E64 is an inhibitor of cysteine proteases. E64 decreases production of IL-8 in vitro.
Cas No. | 66701-25-5 |
---|---|
Purity | ≥99% |
Formula | C15H27N5O5 |
Formula Wt. | 357.41 |
IUPAC Name | (2S,3S)-3-[[(2S)-1-[4-(diaminomethylideneamino)butylamino]-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid |
Solubility | DMSO: ≥ 22 mg/mL; H2O: 36 mg/mL (Need ultrasonic and warming) |
Appearance | White Crystal Powder |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Quain MD, Makgopa ME, Márquez-García B, et al. Ectopic phytocystatin expression leads to enhanced drought stress tolerance in soybean (Glycine max) and Arabidopsis thaliana through effects on strigolactone pathways and can also result in improved seed traits. Plant Biotechnol J. 2014 Apr 22. [Epub ahead of print]. PMID: 24754628.
Lee YA, Nam YH, Min A, et al. Entamoeba histolytica-secreted cysteine proteases induce IL-8 production in human mast cells via a PAR2-independent mechanism. Parasite. 2014;21:1. PMID: 24502918.
Shin SP, Han SY, Han JE, et al. Expression and characterization of cathepsin L-like cysteine protease from Philasterides dicentrarchi. Parasitol Int. 2014 Apr;63(2):359-65. PMID: 24361286.
Steroid hormone involved in stress signaling; g...
Peptide, derivative of AT II, involved in vasoc...
Src and Abl inhibitor.
Endogenous peptide hormone fragment, involved i...
GnRH analog; GnRH1 agonist.
Dihydropyridine; L-type Ca2+ channel blocker.
GPR17 agonist, NMDA and fructose 1,6-bisphospha...
Endogenous cardiomodulatory peptide; NPR-B agon...
Tocopherol analog
FIASMA, 5-HT1/2, M1-5 mAChR, α1-adrenergic, hi...
Fluoroquinolone; bacterial DNA gyrase inhibitor...
Adenosine A2A agonist.
Pim-1 inhibitor.
HDAC6 inhibitor.
Calcineurin inhibitor, potential TRPV1 agonist....
PLK1 inhibitor.
CDK9 inhibitor.
Fluorogenic substrate used to measure serine pr...
Laminin-derived peptapeptide.
Piperadine phenothiazine; FIASMA, D1-5, histami...