Description
E64 is an inhibitor of cysteine proteases. E64 decreases production of IL-8 in vitro.
E64 is an inhibitor of cysteine proteases. E64 decreases production of IL-8 in vitro.
| Cas No. | 66701-25-5 |
|---|---|
| Purity | ≥99% |
| Formula | C15H27N5O5 |
| Formula Wt. | 357.41 |
| IUPAC Name | (2S,3S)-3-[[(2S)-1-[4-(diaminomethylideneamino)butylamino]-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid |
| Solubility | DMSO: ≥ 22 mg/mL; H2O: 36 mg/mL (Need ultrasonic and warming) |
| Appearance | White Crystal Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Quain MD, Makgopa ME, Márquez-García B, et al. Ectopic phytocystatin expression leads to enhanced drought stress tolerance in soybean (Glycine max) and Arabidopsis thaliana through effects on strigolactone pathways and can also result in improved seed traits. Plant Biotechnol J. 2014 Apr 22. [Epub ahead of print]. PMID: 24754628.
Lee YA, Nam YH, Min A, et al. Entamoeba histolytica-secreted cysteine proteases induce IL-8 production in human mast cells via a PAR2-independent mechanism. Parasite. 2014;21:1. PMID: 24502918.
Shin SP, Han SY, Han JE, et al. Expression and characterization of cathepsin L-like cysteine protease from Philasterides dicentrarchi. Parasitol Int. 2014 Apr;63(2):359-65. PMID: 24361286.
Protein translation inhibitor, peptidyl transfe...
Fluoroquinolone, optically active isomer of ofl...
ACE inhibitor.
Iridoid glycoside found in Gardenia.
Topoisomerase II inhibitor, RPA modulator.
β-lactam; penicillin binding protein inhibitor...
Mycotoxin produced by species of Aspergillus; D...
Non-essential amino acid alcohol.
Cholesterol ester transfer protein inhibitor.
Aspirin analog; hemoglobin chain cross-linker.<...
Cap-dependent endonuclease inhibitor
Synthesis intermediate
CRF-related peptide found in amphibians.
Benzyl taxol analog; potential microtubule depo...
Dipeptide; aminopeptidase (N/CD13) inhibitor.
Vitamin D2, ergocalciferol metabolite; VDR agon...
Selective and reversible JAK inhibitor.
Thienopyridine; P2Y12 antagonist.
Aromatase inhibitor.
Thiazolidine macrolide found in the Red Sea spo...