Description
E64 is an inhibitor of cysteine proteases. E64 decreases production of IL-8 in vitro.
E64 is an inhibitor of cysteine proteases. E64 decreases production of IL-8 in vitro.
Cas No. | 66701-25-5 |
---|---|
Purity | ≥99% |
Formula | C15H27N5O5 |
Formula Wt. | 357.41 |
IUPAC Name | (2S,3S)-3-[[(2S)-1-[4-(diaminomethylideneamino)butylamino]-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid |
Solubility | DMSO: ≥ 22 mg/mL; H2O: 36 mg/mL (Need ultrasonic and warming) |
Appearance | White Crystal Powder |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Quain MD, Makgopa ME, Márquez-García B, et al. Ectopic phytocystatin expression leads to enhanced drought stress tolerance in soybean (Glycine max) and Arabidopsis thaliana through effects on strigolactone pathways and can also result in improved seed traits. Plant Biotechnol J. 2014 Apr 22. [Epub ahead of print]. PMID: 24754628.
Lee YA, Nam YH, Min A, et al. Entamoeba histolytica-secreted cysteine proteases induce IL-8 production in human mast cells via a PAR2-independent mechanism. Parasite. 2014;21:1. PMID: 24502918.
Shin SP, Han SY, Han JE, et al. Expression and characterization of cathepsin L-like cysteine protease from Philasterides dicentrarchi. Parasitol Int. 2014 Apr;63(2):359-65. PMID: 24361286.
Synthetic cafestol derivative.
CDK7 inhibitor
An omega-3 fatty acid.
Found in Aristolochia and Radix; potential PLA2...
Nucleoside (guanosine) analog; RT, guanylyl cyc...
Modifies microvascular function
Nucleotide (guanine) analog, prevents guanine s...
Benzimidazole; microtubule polymerization inhib...
Sesquiterpene found in marine sponges.
Alkaline phosphatase substrate used to quantify...
Diclofenac analog, NSAID; COX-2 inhibitor.
Echinocandin
BACE1 inhibitor
G6PDH inhibitor.
NSAID; COX-1/2 inhibitor.
ATP competitive CDK inhibitor.
MEK1/2 inhibitor.
Endogenous glycosaminoglycan that is produced b...
Sialic-acid sensing lectin.
Polyether neurotoxin found in Karenia brevis; N...