Description
E64 is an inhibitor of cysteine proteases. E64 decreases production of IL-8 in vitro.
E64 is an inhibitor of cysteine proteases. E64 decreases production of IL-8 in vitro.
| Cas No. | 66701-25-5 |
|---|---|
| Purity | ≥99% |
| Formula | C15H27N5O5 |
| Formula Wt. | 357.41 |
| IUPAC Name | (2S,3S)-3-[[(2S)-1-[4-(diaminomethylideneamino)butylamino]-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid |
| Solubility | DMSO: ≥ 22 mg/mL; H2O: 36 mg/mL (Need ultrasonic and warming) |
| Appearance | White Crystal Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Quain MD, Makgopa ME, Márquez-García B, et al. Ectopic phytocystatin expression leads to enhanced drought stress tolerance in soybean (Glycine max) and Arabidopsis thaliana through effects on strigolactone pathways and can also result in improved seed traits. Plant Biotechnol J. 2014 Apr 22. [Epub ahead of print]. PMID: 24754628.
Lee YA, Nam YH, Min A, et al. Entamoeba histolytica-secreted cysteine proteases induce IL-8 production in human mast cells via a PAR2-independent mechanism. Parasite. 2014;21:1. PMID: 24502918.
Shin SP, Han SY, Han JE, et al. Expression and characterization of cathepsin L-like cysteine protease from Philasterides dicentrarchi. Parasitol Int. 2014 Apr;63(2):359-65. PMID: 24361286.
Fat-soluble vitamin C derivative.
Polyphenolic compound present in black tea.
Endogenous peptide; FPRL1/2 agonist.
Cathepsin inhibitor.
ITC, erysolin analog.
benzophenanthridine alkaloid found in Chelidoni...
Insect sterilizer; mutagenic.
Venlafaxine metabolite; SERT and NET inhibitor....
Imidazole; 14-α demethylase inhibitor.
Curcumin derivative.
5-HT1A and σ1/2 agonist, 5-HT2A/2C/6/7, D1-4, ...
Broad-spectrum antiviral activity against SARS-...
Peptide, vasopressin analog; V1/2 agonist.
First generation fluoroquinolone antibiotic.
Mycotoxin contaminant found in cereal grains.
Endogenous peptide neurotransmitter, involved i...
Polyphenolic compound present in black tea.
Furanolactone found in citrus fruits.
Peptide, inactive mastoparan analog used to mea...
Endogenous tachykinin peptide, involved in infl...