Description
E64 is an inhibitor of cysteine proteases. E64 decreases production of IL-8 in vitro.
E64 is an inhibitor of cysteine proteases. E64 decreases production of IL-8 in vitro.
| Cas No. | 66701-25-5 |
|---|---|
| Purity | ≥99% |
| Formula | C15H27N5O5 |
| Formula Wt. | 357.41 |
| IUPAC Name | (2S,3S)-3-[[(2S)-1-[4-(diaminomethylideneamino)butylamino]-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid |
| Solubility | DMSO: ≥ 22 mg/mL; H2O: 36 mg/mL (Need ultrasonic and warming) |
| Appearance | White Crystal Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Quain MD, Makgopa ME, Márquez-García B, et al. Ectopic phytocystatin expression leads to enhanced drought stress tolerance in soybean (Glycine max) and Arabidopsis thaliana through effects on strigolactone pathways and can also result in improved seed traits. Plant Biotechnol J. 2014 Apr 22. [Epub ahead of print]. PMID: 24754628.
Lee YA, Nam YH, Min A, et al. Entamoeba histolytica-secreted cysteine proteases induce IL-8 production in human mast cells via a PAR2-independent mechanism. Parasite. 2014;21:1. PMID: 24502918.
Shin SP, Han SY, Han JE, et al. Expression and characterization of cathepsin L-like cysteine protease from Philasterides dicentrarchi. Parasitol Int. 2014 Apr;63(2):359-65. PMID: 24361286.
Nucleobase (adenine) analog; DNA polymerase inh...
Melatonin analog; MT1/2 agonist, 5-HT2C antagon...
Synthetic taxol synthesis intermediate; microtu...
β-lactam; penicillin binding protein inhibitor...
Pentacyclic triterpene found in the Banaba plan...
Synthetic antioxidant that induces phase II enz...
Cysteine-ITC conjugate, antioxidant.
Found in Schisandra.
Active form of vitamin D, regulates dietary Ca2...
CB1 receptor antagonist/ inverse agonist.
Xanthine derivative; PDE inhibitor.
Aza-anthracenedione, DNA intercalator; topoisom...
Aromatase inhibitor.
MAO and histone demethylase LSD1 inhibitor.
Cdc42 inhibitor.
Antioxidant.
CSF-1R Inhibitor.
AMPK activator.
ERK1/2 inhibitor.
Triterpenoid