Description
E64 is an inhibitor of cysteine proteases. E64 decreases production of IL-8 in vitro.
E64 is an inhibitor of cysteine proteases. E64 decreases production of IL-8 in vitro.
| Cas No. | 66701-25-5 |
|---|---|
| Purity | ≥99% |
| Formula | C15H27N5O5 |
| Formula Wt. | 357.41 |
| IUPAC Name | (2S,3S)-3-[[(2S)-1-[4-(diaminomethylideneamino)butylamino]-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid |
| Solubility | DMSO: ≥ 22 mg/mL; H2O: 36 mg/mL (Need ultrasonic and warming) |
| Appearance | White Crystal Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Quain MD, Makgopa ME, Márquez-García B, et al. Ectopic phytocystatin expression leads to enhanced drought stress tolerance in soybean (Glycine max) and Arabidopsis thaliana through effects on strigolactone pathways and can also result in improved seed traits. Plant Biotechnol J. 2014 Apr 22. [Epub ahead of print]. PMID: 24754628.
Lee YA, Nam YH, Min A, et al. Entamoeba histolytica-secreted cysteine proteases induce IL-8 production in human mast cells via a PAR2-independent mechanism. Parasite. 2014;21:1. PMID: 24502918.
Shin SP, Han SY, Han JE, et al. Expression and characterization of cathepsin L-like cysteine protease from Philasterides dicentrarchi. Parasitol Int. 2014 Apr;63(2):359-65. PMID: 24361286.
FIASMA; α1- and β1/2-adrenergic antagonist.
Endogenous APP peptide cleavage product, primar...
14α-demethylase inhibitor.
ANP fragment, natriuretic peptide; Na+/K+ ATPas...
Found in Paeonia, Arisaema, Dioscorea; MAO-A/B ...
Antibiotic
Loop diuretic; NKCC symporter and KCC2 co-trans...
Sulfonamide; PABA inhibitor.
Fluoroquinolone; topoisomerase IV and bacterial...
Lincosamide; ribosomal translocation and protei...
Nucleoside (deoxyguanosine) analog; DNA chain t...
Non-depolarizing NMJ blocker; nAChR and M2/3 mA...
Endogenous peptide hormone, involved in water h...
ALK inhibitor.
VEGFR inhibitor.
FAAH inhibitor.
Endogenous peptide, involved in vascular contra...
ITC, erucin analog.
Endogenous opioid peptide; μOR agonist.
mGluR5 positive modulator.