Enalapril

Name: Enalapril
SKU: E5202
Availability: InStock

Product ID E5202

Cas No. 75847-73-3

Purity ≥98%

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Description

Enalapril is an angiotensin-converting enzyme (ACE) inhibitor that is clinically used to treat hypertension, heart failure, and diabetic nephropathy. Enalapril exhibits antihypertensive activity. Enalapril prevents and reverses renovascular hypertension-induced smooth muscle hypertrophy, collagen deposition, carotid media thickness growth, and other parameters of arterial remodeling. Additionally, enalapril improves endothelial function in migraine sufferers by increasing levels of NO.

Product Info

Cas No.	75847-73-3
Purity	≥98%
Formula	C₂₀H₂₈N₂O₅
Formula Wt.	376.45
Chemical Name	N-[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline
IUPAC Name	(2S)-1-[(2S)-2-[[(2R)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl] pyrrolidine-2-carboxylic acid
Synonym	RenitecR, VasotecR
Melting Point	142-147°C
Solubility	Soluble in water (25mg/L).
Appearance	White Crystal Powder

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

MSDS	E5202 MSDS PDF
Info Sheet	E5202 Info Sheet PDF

References

Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

Bilan VP, Salah EM, Bastacky S, et al. Diabetic nephropathy and long-term treatment effects of rosiglitazone and enalapril in obese ZSF1 rats. J Endocrinol. 2011 Sep;210(3):293-308. PMID: 21680617.

Javanmard SH, Sonbolestan SA, Heshmat-Ghahdarijani K, et al. Enalapril improves endothelial function in patients with migraine: A randomized, double-blind, placebo-controlled trial. J Res Med Sci. 2011 Jan;16(1):26-32. PMID: 21448379.

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Enalapril

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Product Info

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