• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Erucin

Erucin

Product ID E6880
Cas No. 4430-36-8
Purity ≥98%
Product Unit SizeCostQuantityStock
25 mg $183.60 In stock
50 mg $318.70 In stock
100 mg $544.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Erucin is an isothiocyanate (ITC) and analog of sulforaphane found in cruciferous vegetables. Erucin exhibits antioxidative, anti-inflammatory, neuroprotective, anticancer chemotherapeutic, and chemopreventive activities. Like other ITCs, erucin induces phase II enzymes. Erucin also inhibits telomerase and cellular proliferation in hepatocellular carcinoma cells. In animal models of bladder cancer, erucin decreases tumor weight. In animal and cellular models of inflammation, erucin decreases LPS-stimulated expression of IL-6, IL-1β, TNF-α, iNOS, and COX-2. Additionally, this compound decreases ROS and neuronal apoptosis and increases levels of glutathione, preventing 6-OHDA-induced neurodegeneration in cellular models of Parkinson’s disease.

Product Info

Cas No.

4430-36-8

Purity

≥98%

Formula

C6H11NS2

Formula Wt.

161.29

Chemical Name

1-isothiocyanato-4-(methylthio)-butane

IUPAC Name

1-isothiocyanato-4-methylsulfanylbutane

Synonym

4-methylthiobutyl isothiocyanate

Solubility

Soluble in DMSO to 75 mM, and ethanol to 75 mM.

Appearance

Yellow colored liquid

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

E6880 MSDS PDF

Info Sheet

E6880 Info Sheet PDF

Brochures

Erucin Flyer

Brochures

Natural Products Booklet

References

Herz C, Hertrampf A, Zimmermann S, et al. The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC. J Cell Mol Med. 2014 Sep 25. [Epub ahead of print]. PMID: 25256442.

Cho HJ, Lee KW, Park JH. Erucin exerts anti-inflammatory properties in murine macrophages and mouse skin: possible mediation through the inhibition of NFκB signaling. Int J Mol Sci. 2013 Oct 15;14(10):20564-77. dPMID: 24132147.

Tarozzi A, Morroni F, Bolondi C, et al. Neuroprotective Effects of Erucin against 6-Hydroxydopamine-Induced Oxidative Damage in a Dopaminergic-like Neuroblastoma Cell Line. Int J Mol Sci. 2012;13(9):10899-910. PMID: 23109827.

Abbaoui B, Riedl KM, Ralston RA, et al. Inhibition of bladder cancer by broccoli isothiocyanates sulforaphane and erucin: characterization, metabolism, and interconversion. Mol Nutr Food Res. 2012 Nov;56(11):1675-87. PMID: 23038615.

Melchini A, Traka MH. Biological profile of erucin: a new promising anticancer agent from cruciferous vegetables. Toxins (Basel). 2010 Apr;2(4):593-612. PMID: 22069601.

Melchini A, Costa C, Traka M, et al. Erucin, a new promising cancer chemopreventive agent from rocket salads, shows anti-proliferative activity on human lung carcinoma A549 cells. 2009 Jul;47(7):1430-1436. PMID: 19328833.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • V7200

    VS-5584

    PI3K inhibitor.

    ≥98%
  • T6931

    Triclosan

    Diarylether; bacterial ENR binder, fatty acid s...

    ≥98%
  • T1676

    L-Tetrahydropalmatine

    Alkaloid found in Corydalis and Stephania; D1/2...

    ≥98%
  • D3212

    2′,3′-Dideoxycytidine

    Pyrimidine nucleoside (cytidine) analog; DNA ch...

    ≥98%
  • F8048

    Fumagillin

    Produced by Aspergillus; type 2 methionine amin...

    ≥98%
  • A7309

    Ascorbyl Palmitate

    Fat-soluble vitamin C derivative.

    ≥95%
  • C0153

    Calcitonin, rat

    Endogenous neuropeptide hormone, lowers extrace...

    ≥95%
  • T2402

    TG100-115

    p110δ and p110γ PI3K inhibitor.

    ≥98%
  • V3276

    Vitamin E, Natural

    Antioxidant.

    ≥97%
  • I7457

    1-Isothiocyanato-6-(methylsulfinyl)-hexane

    Synthetic derivative of 6-methylsulfinyl-hexane...

    ≥98%
  • T3310

    Ticlopidine Hydrochloride

    Thienopyridine; P2Y12 antagonist.

    ≥98%
  • T1002

    2-Debenzoyl Paclitaxel-2-(2-Methyl-2-Butenoate)

    Synthesis intermediate

    ≥95%
  • S8144

    Sulfadoxine

    Sulfonamide; dihydropteroate synthase inhibitor...

    ≥98%
  • B1653

    Benzyl Isothiocyanate

    ITC found in cruciferous vegetables.

    ≥99%
  • S3568

    Siramesine

    σ2 agonist.

    ≥98%
  • E537333

    Enniatin A1

    Mycotoxin contaminant found in cereal grains.

    ≥98%
  • G5874

    Gossypol

    Polyphenol found in Gossypium; calcineurin and ...

    ≥98%
  • E5358

    Enoxacin

    Fluoroquinolone; vacuolar H+ ATPase, topoisomer...

    ≥98%
  • C0376

    Catharanthine base

    Alkaloid found in Catharanthus, precursor in sy...

    ≥98%
  • I538583

    Inosine

    Adenosine analog

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only