Description
GBR-12909 is a potent and selective dopamine reuptake inhibitor (DRI). In a mouse model it has been found to increase activity and reduce spatial d in combination with increased exploratory behavior.
GBR-12909 Dihydrochloride
Product ID G062680
Cas No. 67469-78-7
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 67469-78-7 |
|---|---|
| Purity | ≥98% |
| Formula | C28H32F2N2O • 2HCl |
| Formula Wt. | 523.49 |
| Chemical Name | 1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)piperazine dihydrochloride |
| IUPAC Name | 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine;dihydrochloride |
| Synonym | Vanorexine Dihydrochloride, Vanoxerine hydrochloride |
| Solubility | Slightly soluble in water ~2.5 mg/mL. Solubility in DMSO - >25 mg/mL. |
Shipping and Storage
| Store Temp | Ambient |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Andersen P. The dopamine inhibitor GBR 12909: selectivity and molecular mechanism of action. Eur J Pharmacol. 166(3):493-504 (1989). PMID: 2530094.
Young J, Goey A, Minassian A, et al. GBR 12909 administration as a mouse model of bipolar disorder mania: mimicking quantitative assessment of manic behavior. Psychopharmacology (Berl). 2010 Feb;208(3):443-454. PMID: 20020109.