• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Indolicidin

Indolicidin

Product ID I5215
Cas No. 140896-21-5
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $126.00 In stock
1 mg $207.90 In stock
2.5 mg $336.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Indolicidin is an antimicrobial peptide (AMP) that interacts with and disrupts membranes. Indolicidin binds negatively charged lipid membranes and induces release of vesicle contents but does not form pores like other AMPs. Indolicidin exhibits antibacterial, hemolytic, and anti-inflammatory activities. This peptide displays antibiotic activity against both gram positive and gram negative bacteria, inhibiting growth of Acinetobacter, Staphyloccocus, and Nocardia, among others. Additionally, indolicidin inhibits production of NO and iNOS in LPS-stimulated macrophages and inhibits production of TNF-α in various other cell lines.

Product Info

Cas No.

140896-21-5

Purity

≥95%

Formula

C100H132N26O13

Formula Wt.

1906.33

Solubility

Soluble in water (1 mg/mL), DMSO.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

I5215 MSDS PDF

Info Sheet

I5215 Info Sheet PDF

References

Vila-Farres X, Garcia de la Maria C, López-Rojas R, et al. In vitro activity of several antimicrobial peptides against colistin-susceptible and colistin-resistant Acinetobacter baumannii. Clin Microbiol Infect. 2012 Apr;18(4):383-7. PMID: 21672084.

Végh AG, Nagy K, Bálint Z, et al. Effect of antimicrobial peptide-amide: indolicidin on biological membranes. J Biomed Biotechnol. 2011;2011:670589. PMID: 21765635.

Rieg S, Kaasch AJ, Wehrle J, et al. Susceptibility of clinical Staphylococcus aureus isolates to innate defense antimicrobial peptides. Microbes Infect. 2011 Aug;13(8-9):761-5. PMID: 21473929.

Rokitskaya TI, Kolodkin NI, Kotova EA, et al. Indolicidin action on membrane permeability: carrier mechanism versus pore formation. Biochim Biophys Acta. 2011 Jan;1808(1):91-7. PMID: 20851098.

Rieg S, Meier B, Fähnrich E, et al. Differential activity of innate defense antimicrobial peptides against Nocardia species. BMC Microbiol. 2010 Feb 23;10:61. PMID: 20178618.

Nan YH, Park KH, Park Y, et al. Investigating the effects of positive charge and hydrophobicity on the cell selectivity, mechanism of action and anti-inflammatory activity of a Trp-rich antimicrobial peptide indolicidin. FEMS Microbiol Lett. 2009 Mar;292(1):134-40. PMID: 19191872.

Bowdish DM, Davidson DJ, Scott MG, et al. Immunomodulatory activities of small host defense peptides. Antimicrob Agents Chemother. 2005 May;49(5):1727-32. PMID: 15855488.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • G4532

    Gliclazide

    Sulfonylurea; SUR1 antagonist.

    ≥98%
  • E7578

    Estramustine

    Nitrogen mustard and estradiol derivative; micr...

    ≥97%
  • F1670

    Ferulic Acid Methyl Ester

    Hydroxycinnamic aicd, verbascoside metabolite, ...

    ≥98%
  • S761025

    Stauprimide

    Analog of staurosporine.

    ≥98%
  • V9201

    VX-11e

    ERK2 inhibitor, potential AurKA, GSK3, CDK2, FL...

    ≥98%
  • A9435

    Axitinib

    VEGFR inhibitor.

    ≥98%
  • K1678

    Ketanserin

    5-HT2A antagonist, potential α1-adrenergic ant...

    ≥97%
  • T0106

    Xylosyltaxol

    Taxane found in species of Taxus; potential mic...

    ≥98%
  • D1777

    Desmopressin Acetate

    Synthetic peptide, vasopressin derivative; V2 a...

    ≥95%
  • I0801

    IC261

    Casein kinase 1 inhibitor.

    ≥98%
  • M185777

    4-(Methylsulfinyl) butylamine

    ≥99%
  • T3454

    Tinidazole

    Nitroimidazole, binds DNA; nucleic acid synthes...

    ≥98%
  • F8151

    Fumonisin B3

    Mycotoxin produced by Fusarium fungi that infec...

    ≥98%
  • V1810

    Vecuronium Bromide

    Non-depolarizing NMJ blocker; nAChR antagonist....

    ≥98%
  • A9912

    AZD-7762 Hydrochloride

    CHK1 inhibitor.

    ≥98%
  • P1854

    Penicillic Acid

    Neuroactive mycotoxin produced by Penicillum an...

    ≥98%
  • K0040

    Kahweol Stearate

    Diterpene found in coffee beans.

    ≥98%
  • M1680

    5-Methoxyindole

    Core structure of melatonin; potential PPARγ a...

    ≥98%
  • G0106

    Gabapentin

    GABA analog; GABA potentiator, adenosine A1 ago...

    ≥98%
  • C3263

    Ciprofloxacin Hydrochloride Monohydrate

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only