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Metoprolol Tartrate

Product ID M1879
Cas No. 56392-17-7
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $64.90 In stock
25 g $231.50 In stock
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  • Description
  • Product Info
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  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Metoprolol is an inhibitor of β1-adrenergic receptors that exhibits antihypertensive, cardioprotective, anti-anginal, class II anti-arrhythmic, anti-atherosclerotic, anti-inflammatory, anticonvulsant/antiepileptic, and pro-angiogenic activities. Metoprolol is clinically used to treat hypertension, myocardial infarction, tachycardia, and congestive heart failure (CHF). In animal models of atherosclerosis, metoprolol decreases levels of TNF-α and CXCL1, infiltration of macrophages, and size of atherosclerotic plaques. This compound also inhibits seizures in animal models and, separately, increases microvessel sprouting in aortic rings.

Product Info

Cas No.

56392-17-7

Purity

≥98%

Formula

(C15H25NO3)2 • C4H6O6

Formula Wt.

684.82

Chemical Name

1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)- amino]-2-propanol tartrate

IUPAC Name

(2R,3R)-2,3-dihydroxybutanedioic acid;1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol

Synonym

Beloc, Betaloc, Lopressor, Prelis, Seloken, Selopral, Selo-Zok

Melting Point

120°C

Solubility

Soluble in water, methanol, ethanol, DMSO, or chloroform.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

M1879 MSDS PDF

Info Sheet

M1879 Info Sheet PDF

References

Ulleryd MA, Bernberg E, Yang LJ, et al. Metoprolol Reduces Proinflammatory Cytokines and Atherosclerosis in ApoE(-/-) Mice. Biomed Res Int. 2014;2014:548783. PMID: 25105129.

Borowicz KK, Banach M. Antiarrhythmic drugs and epilepsy. Pharmacol Rep. 2014 Aug;66(4):545-51. PMID: 24948053.

Stati T, Musumeci M, Maccari S, et al. β-Blockers promote angiogenesis in the mouse aortic ring assay. J Cardiovasc Pharmacol. 2014 Jul;64(1):21-7. PMID: 24621648.

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