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Ochratoxin A

Ochratoxin A

Product ID O0829
Cas No. 303-47-9
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $135.70 In stock
5 mg $589.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ochratoxin A is a mycotoxin initially produced by Aspergillus and Penicillum that exhibits carcinogenic, neurotoxic, and pro-fibrotic activities. Ochratoxin A is occasionally found as a contaminant in food and livestock feed. In vivo, ochratoxin A inhibits glial cell proliferation, induces kidney damage and collagen formation, and potentially increases the development of cancerous formations.

Product Info

Cas No.

303-47-9

Purity

≥98%

Formula

C20H18ClNO6

Formula Wt.

403.82

Chemical Name

(R)-N-[(5-Chloro-3,4-dihydro-8-hydroxy-3-methyl-1- oxo-1H-2benzopyran-7-yl)carbonyl]-L-phenylalanine

IUPAC Name

(2S)-2-[[(3R)-5-chloro-8-hydroxy-3-methyl-1-oxo-3, 4-dihydroisochromene-7-carbonyl]amino]-3-phenylpropanoic acid

Synonym

Phenylalanine - ochratoxin A

Melting Point

169°C

Solubility

Soluble in methanol (10 mg/mL), ethanol (20 mg/mL).

Appearance

White to off white crystals

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

O0829 MSDS PDF

Info Sheet

O0829 Info Sheet PDF

References

Hennemeier I, Humpf HU, Gekle M, et al. Role of microRNA-29b in the ochratoxin A-induced enhanced collagen formation in human kidney cells. Toxicology. 2014 Oct 3;324:116-22. PMID: 25091173.

Paradells S, Rocamonde B, Llinares C, et al. Neurotoxic effects of ochratoxin A on the subventricular zone of adult mouse brain. J Appl Toxicol. 2014 Sep 25. [Epub ahead of print]. PMID: 25256750.

Qi X, Yu T, Zhu L, et al. Ochratoxin A induces rat renal carcinogenicity with limited induction of oxidative stress responses. Toxicol Appl Pharmacol. 2014 Sep 8. [Epub ahead of print]. PMID: 25218026.

Wu X, Hu J, Zhu B, et al. Aptamer-targeted magnetic nanospheres as a solid-phase extraction sorbent for determination of ochratoxin A in food samples. J Chromatogr A. 2011 Oct 14;1218(41):7341-7346. PMID: 21890142.

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