Description
Paclitaxel, 8-Hydro-bicylo(3.3.0)octane is an impurity of the chemotherapy drug paclitaxel. It is a photodegradant impurity.
Paclitaxel, 8-Hydro-bicyclo(3.3.0)octane
Product ID T1028
Cas No. 146139-03-9
Purity ≥95%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 146139-03-9 |
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| Purity | ≥95% |
| Formula | C47H51NO14 |
| Formula Wt. | 853.92 |
| Chemical Name | Paclitaxel, 8-Hydro-bicyclo(3.3.0)octane |
| IUPAC Name | [2,10-diacetyloxy-15-(3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy-5,13-dihydroxy-4,16,17,17-tetramethyl-3-oxo-8-oxapentacyclo[11.3.1.01,11.04,11.07,10]heptadecan-12-yl] benzoate |
| Synonym | Paclitaxel Photodegradant; Photodegradant of Paclitaxel, Paclitaxel Impurity 21, BCP33132 |
Shipping and Storage
| Store Temp | -80°C |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Nicolaou K, Yang Z, Liu J, et al. Total synthesis of taxol. Nature. 1994 Feb 17;367(6464):630-634. PMID: 7906395.
Nicolaou K, Valiulin R. Synthesis and biological evaluation of new paclitaxel analogs and discovery of potent antitumor agents. Org Biomol Chem. 2013 Jul 7;11(25):4154-4163. PMID: 23685867.
Sanchez-Munoz R, Perez-Mata E, Almagro L, et al. A novel hydroxylation step in the taxane biosynthetic pathway: a new approach to paclitaxel production by synthetic biology. Front Bioeng Biotechnol. 2020 May 13;8::410. PMID: 32528936.
Guo B, Kai G, Jin H, et al. Taxol synthesis. African J Biotechnol. 2006 Jan 2;5(1):15-20.
Wang T, Chen Y, Zhuang W, et al. Transcriptome sequencing reveals regulatory mechanisms of taxol synthesis in Taxus wallichiana var. Mairei. Int J Genomics. 2019 May 2;2019:1596895. PMID: 31192250.