Description
PHT-427 is an inhibitor of PDK1 and Akt that exhibits anticancer chemotherapeutic activity, inhibiting tumor growth in animal models of breast cancer and non-small cell lung cancer (NSCLC).
Product Unit Size | Cost | Quantity | Stock |
---|
PHT-427 is an inhibitor of PDK1 and Akt that exhibits anticancer chemotherapeutic activity, inhibiting tumor growth in animal models of breast cancer and non-small cell lung cancer (NSCLC).
Cas No. | 1191951-57-1 |
---|---|
Purity | ≥98% |
Formula | C20H31N3O2S2 |
Formula Wt. | 409.61 |
Chemical Name | 4-Dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide |
IUPAC Name | 4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide |
Synonym | PHT427; PHT 427 |
Solubility | DMSO 82 mg/mL (200.19 mM) Ethanol 60 mg/mL (146.48 mM) Water Insoluble |
Appearance | White Crystal Powder |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet | |
Brochures |
Meuillet EJ, Zuohe S, Lemos R, et al. Molecular pharmacology and antitumor activity of PHT-427, a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor. Mol Cancer Ther. 2010 Mar;9(3):706-17. PMID: 20197390.
Trichothecene mycotoxin produced by Fusarium, a...
Triterpene saponin found in species of Panax.
Indole, glucosinolate found in cruciferous vege...
Aromatic 1,3-diketone acetylacetone derivative ...
AMPK activator.
Extract containing catechins and flavonoids fou...
Pleuromutilin
Cytarabine derivative, nucleoside (cytosine) an...
Endogenous thyroid hormone T4.
Cysteine-ITC conjugate, antioxidant.
Read-through agent and nonsense mutation target...
Docetaxel impurity
β-lactam; penicillin binding protein inhibitor...
Selective inhibitor of protein kinase C (PKC).<...
Nucleotide (guanine) analog, prevents guanine s...
Endogenous peptide hormone, involved in intesti...
Aminoglycoside; protein translation inhibitor, ...
Antimicrobial found in essential oils from plan...
Bisphosphonate; FPPS inhibitor.
β-adrenergic antagonist, Kv1.4 and K2P2 K+ cha...