STING Agonist-12

Name: STING Agonist-12
SKU: S771339
Availability: InStock

Product ID S771339

Cas No. 2259624-71-8

Purity ≥99%

Product Unit Size	Cost	Quantity		Stock

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Description
Product Info
Shipping and Storage
Downloads
References

Description

STING Agonist-12 is an activator of STING.

Product Info

Cas No.	2259624-71-8
Purity	≥99%
Formula	C₂₅H₁₉ClF₄N₂O₂
Formula Wt.	490.88
IUPAC Name	1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]indole-6-carboxamide
Synonym	Compound 53, STING Agonist C53, GTPL11960
Appearance	White powder

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

Info Sheet	S771339 Info Sheet PDF

References

Pryde D, Middya S, Banerjee M, et al. The discovery of potent small molecule activators of human STING. Eur J Med Chem. 2021 Jan 1;209:112869. PMID: 33038794

Lu D, Shang G, Li J, et al. Activation of STING by targeting a pocket in the transmembrane domain. Nature. 2022 Apr;604(7906):557-562. PMID: 35388221

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