• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register

Daptomycin

Product ID D0363
Cas No. 103060-53-3
Purity ≥97%
Product Unit SizeCostQuantityStock
5 mg $45.00 In stock
25 mg $120.00 In stock
100 mg $298.00 In stock
Bulk Quote
Add to Wishlist

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Daptomycin is an anionic lipopeptide antibiotic that exhibits antibacterial efficacy and is used clinically to treat gram positive bacterial infections such as MRSA. Daptomycin induces reorganization of cell membranes and alters localization of proteins involved in cell division and cell wall synthesis; this compound also induces release of intracellular Ca2+ and other ions. This compound is also produced by the soil saprotroph Streptomyces roseosporus.

Product Info

Cas No.

103060-53-3

Purity

≥97%

Formula

C72H101N17O26

Formula Wt.

1620.67

Chemical Name

N-decanoyl-L-tryptophyl-L-asparaginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-seryl-threo -3-methyl-L-glutamyl-3-anthraniloyl-L-alanine[egr]1-lactone

Solubility

Soluble in ethanol (50 mM), methano, DMF, DMSO (100 mM). Slightly soluble in water (25 mg/mL, 5 mM).

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

D0363 MSDS PDF

Info Sheet

D0363 Info Sheet PDF

References

Pogliano J, Pogliano N, Silverman JA. Daptomycin-mediated reorganization of membrane architecture causes mislocalization of essential cell division proteins. J Bacteriol. 2012 Sep;194(17):4494-504. PMID: 22661688.

Vilhena C, Bettencourt A. Daptomycin: a review of properties, clinical use, drug delivery and resistance. Mini Rev Med Chem. 2012 Mar;12(3):202-9. PMID: 22356191

Beiras-Fernandez A, Vogt F, Sodian R, et al. Daptomycin: a novel lipopeptide antibiotic against Gram-positive pathogens. Infect Drug Resist. 2010;3:95-101. PMID: 21694898.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2023 LKT Laboratories, All Rights Reserved - Products for research use only