| Product Unit Size | Cost | Quantity | Stock |
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Cyclosporin D is a cyclosporin metabolite that weakly inhibits calmodulin and displays little immunosuppressive activity. Cyclosporin D exhibits anti-parasitic and antimalarial activities, inhibiting Plasmodium development in vitro and in vivo.
| Cas No. | 63775-96-2 |
|---|---|
| Purity | ≥98% |
| Formula | C63H113N11O12 |
| Formula Wt. | 1216.64 |
| IUPAC Name | (3S,6S,9S,12R,15S,18S,21S,24S,30S)-33-[(E,1R, 2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6, 9,18,24-tetrakis(2-methylpropyl)-3,21,30-tri(propan-2-yl)-1,4,7,10,13, 16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26, 29,32-undecone |
| Synonym | Val2-cyclosporine |
| Melting Point | 148-151°C |
| Solubility | Soluble in methanol, ethanol, acetone, ether, ethyl acetate or chloroform. Insoluble in water. |
| Appearance | White Crystalline Powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Uadia PO, Ezeamuzie IC, Ladan MJ, et al. Antimalarial activity of cyclosporins A, C and D. Afr J Med Med Sci. 1994 Mar;23(1):47-51. PMID: 7839946.
Sadeg N, Pham-Huy C, Rucay P, et al. In vitro and in vivo comparative studies on immunosuppressive properties of cyclosporines A, C, D and metabolites M1, M17 and M21. Immunopharmacol Immunotoxicol. 1993 Mar-Jun;15(2-3):163-77. PMID: 8349948.