Description
Baccatin VI is an impurity of the chemotherapy drug paclitaxel.
Product Unit Size | Cost | Quantity | Stock |
---|
Baccatin VI is an impurity of the chemotherapy drug paclitaxel.
Cas No. | 57672-79-4 |
---|---|
Purity | ≥98% |
Formula | C37H46O14 |
Formula Wt. | 714.75 |
Chemical Name | Baccatin VI |
IUPAC Name | [(1S,2S,3R,4S,7R,9S,10S,11R,12R,15S)-4,9,11,12,15-pentaacetyloxy-1-hydroxy-10,14,17,17-tetramethyl-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate |
Synonym | (2aR,4S,4aS,5R,6R,9S,11S,12S,12aR,12bS)-2a,3,4,4a,5,6,9,10,12,12a-Decahydro-4a,8,13,13-tetramethyl-4,5,6,9,12b-pentaacetate 12-Benzoate Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-4,5,6,9,11,12,12b-heptol |
Appearance | White to off-white powder |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Nicolaou K, Yang Z, Liu J, et al. Total synthesis of taxol. Nature. 1994 Feb 17;367(6464):630-634. PMID: 7906395.
Nicolaou K, Valiulin R. Synthesis and biological evaluation of new paclitaxel analogs and discovery of potent antitumor agents. Org Biomol Chem. 2013 Jul 7;11(25):4154-4163. PMID: 23685867.
Sanchez-Munoz R, Perez-Mata E, Almagro L, et al. A novel hydroxylation step in the taxane biosynthetic pathway: a new approach to paclitaxel production by synthetic biology. Front Bioeng Biotechnol. 2020 May 13;8::410. PMID: 32528936.
Guo B, Kai G, Jin H, et al. Taxol synthesis. African J Biotechnol. 2006 Jan 2;5(1):15-20.
Wang T, Chen Y, Zhuang W, et al. Transcriptome sequencing reveals regulatory mechanisms of taxol synthesis in Taxus wallichiana var. Mairei. Int J Genomics. 2019 May 2;2019:1596895. PMID: 31192250.
Cyclohexanecarboxylic acid found in various pla...
NSAID; COX-1/2 inhibitor.
Taxane found in Taxus; microtubule depolymeriza...
PLK1 inhibitor.
Staurosporine analog; PKC and PKA inhibitor.
Phenylethanoid glycoside found in Echinacea.
Ornithine decarboxylase inhibitor.
Inhibitor of PTEFb/CDK9.
AMPA antagonist.
MEK1/2 and ERK inhibitor.
Phenothiazine derivative; D1/2 and 5-HT1A/2A an...
Broad-spectrum antibiotic
FGFR inhibitor.
RF-amide peptide; potential GPR147 agonist, pot...
Coumarin, more potent isomer; VKORC1 inhibitor....
Endogenous peptide hormone inolved in gastric e...
Furan derivative.
Peptide, derivative of AT I, cleavage product o...
Omega-6 fatty acid found in vegetable oils; PPA...
PARP1/2 inhibitor.