Cetrorelix Acetate

Name: Cetrorelix Acetate
SKU: C1879
Availability: BackOrder

Product ID C1879

Cas No. 130143-01-0

Purity ≥95%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Cetrorelix is a gonadotropin-releasing hormone (GnRH) analog that inhibits LHRH and GnRH. Cetrorelix exhibits anti-inflammatory activity and has been used clinically as a treatment for infertility due to its suppression of FSH and LH levels. In animal models of benign prostatic hyperplasia (BPH), cetrorelix decreases levels of inflammatory cytokines and growth factors, decreasing prostate size and weight. Additionally, cetrorelix decreases levels of Bax, caspase 3, and cytochrome c, inhibiting chemotherapy-induced mitochondria-dependent apoptosis in granulosa cells in vivo.

Product Info

Cas No.	130143-01-0
Purity	≥95%
Formula	C₇₀H₉₂N₁₇O₁₄
Formula Wt.	1431.06
IUPAC Name	(2S)-1-[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-[[ (2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl) propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl] amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-(carbamoylamino)pentanoyl] amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N- [(2R)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
Synonym	Cetrelix Acetate, Cetrorenlin Acetate
Solubility	Soluble in DMSO.

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

MSDS	C1879 MSDS PDF
Info Sheet	C1879 Info Sheet PDF

References

Rick FG, Schally AV, Block NL, et al. LHRH antagonist Cetrorelix reduces prostate size and gene expression of proinflammatory cytokines and growth factors in a rat model of benign prostatic hyperplasia. Prostate. 2011 May 15;71(7):736-47. PMID: 20945403.

Zhao XJ, Huang YH, Yu YC, et al. GnRH antagonist cetrorelix inhibits mitochondria-dependent apoptosis triggered by chemotherapy in granulosa cells of rats. Gynecol Oncol. 2010 Jul;118(1):69-75. PMID: 20417958.

Reissmann T, Felberbaum R, Diedrich K, et al. Development and applications of luteinizing hormone-releasing hormone antagonists in the treatment of infertility: an overview. Hum Reprod. 1995 Aug;10(8):1974-81. PMID: 8567825.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Phone
This field is for validation purposes and should be left unchanged.

Cetrorelix Acetate

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

AT-7519 free base

Nimorazole

Inositol

PCI-32765

Disodium Cycloheptylaminomethylene Diphosphate

Prolylrapamycin

Sulindac Sulfide

CCG1423

Bitertanol

Carnosol

Dalcetrapib

Pranoprofen

4-α-Phorbol-12-myristate-13-acetate

Teicoplanin

Teniposide

S-Methyl-L-cysteine-S-oxide

GSK-2982772

Chenodeoxycholic Acid

Calcitonin Gene Related Peptide (8-37), human

Lofexidine Hydrochloride

Footer