LKT Labs

Biochemicals for Life Science Research

Cetrorelix Acetate

Cetrorelix Acetate

Product ID C1879
Cas No. 130143-01-0
Purity ≥95%
Product Unit SizeCostQuantityStock
50 mg $1,968.00 Please Inquire
100 mg $2,679.00 Please Inquire
Bulk Quote

Quicklinks

Description

Cetrorelix is a gonadotropin-releasing hormone (GnRH) analog that inhibits LHRH and GnRH. Cetrorelix exhibits anti-inflammatory activity and has been used clinically as a treatment for infertility due to its suppression of FSH and LH levels. In animal models of benign prostatic hyperplasia (BPH), cetrorelix decreases levels of inflammatory cytokines and growth factors, decreasing prostate size and weight. Additionally, cetrorelix decreases levels of Bax, caspase 3, and cytochrome c, inhibiting chemotherapy-induced mitochondria-dependent apoptosis in granulosa cells in vivo.

Product Info

Cas No.

130143-01-0
Purity

≥95%
Formula

C70H92N17O14
Formula Wt.

1431.06
IUPAC Name

(2S)-1-[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-[[ (2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl) propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl] amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-(carbamoylamino)pentanoyl] amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N- [(2R)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
Synonym

Cetrelix Acetate, Cetrorenlin Acetate
Solubility

Soluble in DMSO.

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

C1879 MSDS PDF
Info Sheet

C1879 Info Sheet PDF

References

Rick FG, Schally AV, Block NL, et al. LHRH antagonist Cetrorelix reduces prostate size and gene expression of proinflammatory cytokines and growth factors in a rat model of benign prostatic hyperplasia. Prostate. 2011 May 15;71(7):736-47. PMID: 20945403.

Zhao XJ, Huang YH, Yu YC, et al. GnRH antagonist cetrorelix inhibits mitochondria-dependent apoptosis triggered by chemotherapy in granulosa cells of rats. Gynecol Oncol. 2010 Jul;118(1):69-75. PMID: 20417958.

Reissmann T, Felberbaum R, Diedrich K, et al. Development and applications of luteinizing hormone-releasing hormone antagonists in the treatment of infertility: an overview. Hum Reprod. 1995 Aug;10(8):1974-81. PMID: 8567825.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A9710

    AZD-2014

    mTOR inhibitor.

    ≥98%
  • T1675

    Teriparatide Acetate

    Synthetic peptide hormone, PTH analog; PTH1R ag...

    ≥95%
  • A761001

    AT-7519 free base

    ATP competitive CDK inhibitor.

    ≥98%
  • T1008

    10,13-Bissidechain Paclitaxel

    Synthesis impurity

    ≥90%
  • N0263

    Naphazoline Nitrate

    α1-adrenergic agonist.

    ≥97%
  • C0140

    Calcitonin, eel

    Endogenous neuropeptide hormone, lowers extrace...

    ≥95%
  • L5751

    Lomerizine Dihydrochloride

    L-type and T-type Ca2+ and TRP antagonist.

    ≥98%
  • H0207

    Hepatitis B Virus Core Protein (128-140)

    B cell epitope found on hepatitis B viral core ...

    ≥95%
  • L186860

    Levomefolic acid calcium salt

    Folic acid derivative

    ≥98%
  • S164098

    Seco-rapamycin

    Rapamycin analog

    ≥73%
  • M1874

    3-Methyladenine

    Nucleobase (adenine) analog; DNA polymerase inh...

    ≥98%
  • D3449

    Dimethoxycurcumin

    Curcumin derivative.

    ≥98%
  • I5208

    INCB-28060

    c-MET inhibitor.

    ≥98%
  • P3463

    Piperacillin Sodium

    β-lactam; penicillin binding protein inhibitor...

    ≥95%
  • E5216

    β-Endorphin, camel

    Endogenous opioid peptide; μOR agonist.

    ≥95%
  • P1852

    Penicillin G procaine

    Hydrophobic β-lactam; penicillin binding prote...

    ≥98%
  • L0248

    Laminin Peptide YIGSR

    Laminin-derived peptapeptide.

    ≥98%
  • P0256

    Pantoprazole Sodium Sesquihydrate

    H+/K+ ATPase and ROCK-2 inhibitor.

    ≥98%
  • A851322

    Avibactam Sodium

    Diazabicyclooctane β-lactamase inhibitor.

    ≥98%
  • D3431

    3,4-Dihydroxyphenyl Ethanol

    Polyphenol found in olive oil, antioxidant.

    ≥95%