LKT Labs

Biochemicals for Life Science Research

Verbascoside

Verbascoside

Product ID V1869
Cas No. 61276-17-3
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $128.00 In stock
5 mg $245.00 In stock
10 mg $367.00 In stock
25 mg $715.00 In stock
Bulk Quote

Quicklinks

Description

Verbascoside is a phenylpropanoid found in a variety of species of Castilleja, Verbena, and Verbascum. Verbascoside displays anti-inflammatory, analgesic, antioxidative, and antithrombotic properties in a variety of cellular and animal models. In vitro, verbascoside inhibits arachidonic acid- and ADP-induced platelet aggregation as well as dipeptidyl peptidase 4 (DPP4) and prolyl oligopeptidase activity. In vivo, verbascoside decreases levels of Bax, Bcl-2, NF-κB, iNOS, and myeloperoxidase, showing anti-inflammatory benefit in a model of periodontitis. Additionally, this compound inhibits mechanical pain in two different animal models of hyperalgesia. Verbascoside may also be an inhibitor of PKC.

Product Info

Cas No.

61276-17-3
Purity

≥98%
Formula

C29H36O15

Formula Wt.

624.59
Chemical Name

[(2R,3R,4R,5R,6R)-6-[2-(3, 4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R, 6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
IUPAC Name

[(2R,3R,4R,5R,6R)-6-[2-(3, 4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R, 6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
Synonym

Acteoside, Kusaginin
Appearance

Off-white powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

V1869 MSDS PDF
Info Sheet

V1869 Info Sheet PDF

References

Campo G, Marchesini J, Bristot L, et al. The in vitro effects of verbascoside on human platelet aggregation. J Thromb Thrombolysis. 2012 Oct;34(3):318-25. PMID: 22723176.

Filho AG, Morel AF, Adolpho L, et al. Inhibitory effect of verbascoside isolated from Buddleja brasiliensis Jacq. ex Spreng on prolyl oligopeptidase activity. Phytother Res. 2012 Oct;26(10):1472-5. PMID: 22275311.

Paola RD, Oteri G, Mazzon E, et al. Effects of verbascoside, biotechnologically purified by Syringa vulgaris plant cell cultures, in a rodent model of periodontitis. J Pharm Pharmacol. 2011 May;63(5):707-17. PMID: 21492173.

Isacchi B, Iacopi R, Bergonzi MC, et al. Antihyperalgesic activity of verbascoside in two models of neuropathic pain. J Pharm Pharmacol. 2011 Apr;63(4):594-601. PMID: 21401613.

Kahraman C, Tatli II, Orhan IE, et al. Cholinesterase inhibitory and antioxidant properties of Verbascum mucronatum Lam. and its secondary metabolites. Z Naturforsch C. 2010 Nov-Dec;65(11-12):667-74. PMID: 21319708.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • O938582

    41-Oxo-rapamycin

    Impurity of rapamycin

    ≥95%
  • I7870

    Itraconazole

    Triazole; 14-α demethylase inhibitor, Smo modu...

    ≥98%
  • R3220

    Rifampicin

    Ansamycin; bacterial DNA-dependent RNA polymera...

    ≥98%
  • C3446

    Cilnidipine

    Dihydropyridine; L-type and N-type Ca2+ channel...

    ≥98%
  • C179603

    CEP-37440 Hydrochloride

    Inhibitor of FAK and ALK.

    ≥99%
  • M2408

    MGCD-265 Analog

    MET inhibitor.

    ≥98%
  • L3551

    Limonin Glucoside

    Furanolactone found in Citrus.

    ≥95%
  • A9834

    Azithromycin Dihydrate

    Azalide macrolide; protein translation inhibito...

    ≥98%
  • K0031

    Kahweol Acetate

    Diterpene found in coffee beans.

    ≥98%
  • I7759

    Isoxanthohumol

    Prenylflavinoid, derivative of xanthohumol foun...

    ≥98%
  • A0918

    N-Acetyl-L-Cysteine

    Cysteine derivative, antioxidant, ROS scavenger...

    ≥98%
  • D0004

    Dabrafenib

    B-Raf and c-Raf inhibitor.

    ≥98%
  • R1780

    trans-Retinoic Acid

    Vitamin A carboxylic acid; RAR agonist.

    ≥98%
  • B1746

    Belinostat

    HDAC inhibitor.

    ≥98%
  • T0092

    1-Hydroxybaccatin I

    Diterpene found in Taxus; potential microtubule...

    ≥96%
  • M017545

    Manumycin A

    Natural antibiotic found in Streptomyces parvul...

    ≥98%
  • T1849

    Temozolomide

    Imidazotetrazine, DNA alkylator.

    ≥98%
  • N3228

    Nifedipine

    Dihydropyridine; L-type Ca2+ channel blocker.

    ≥98%
  • B1753

    Benfotiamine

    Thiamine/vitamin B derivative, antioxidant.

    ≥98%
  • A6268

    Aprotinin

    Polypeptide; serine protease inhibitor.

    ≥ 5400 u/mg