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Adrenocorticotropic Hormone (1-16), human

Product ID A0966
Cas No. 5576-42-1
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $103.70 In stock
1 mg $178.00 In stock
2.5 mg $311.60 In stock
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  • Description
  • Product Info
  • Shipping and Storage
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  • References
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Description

Adrenocorticotropic hormone (ACTH) is a peptide derived from proopiomelanocortin (POMC) processed and secreted in the pituitary gland. ACTH binds and activates melanocortin-2 (MC2) receptors, stimulating cortisol production in the adrenal cortex. ACTH exhibits anti-inflammatory and immunomodulatory activities. ACTH decreases inflammatory cytokine levels and modulates lymphocyte and macrophage functions. In vitro, ACTH stimulates proliferation of osteoblasts and increases mRNA levels of collagen I.

Product Info

Cas No.

5576-42-1

Purity

≥95%

Formula

C89H133N25O22S

Formula Wt.

1937.27

Synonym

ACTH (1-16)

Solubility

Soluble in water.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

A0966 Info Sheet PDF

References

Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

Custom Order

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