• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Sumatriptan Succinate

Sumatriptan Succinate

Product ID S8151
Cas No. 103628-48-4
Purity ≥99%
Product Unit SizeCostQuantityStock
25 mg $112.60 In stock
100 mg $211.40 In stock
250 mg $408.50 In stock
1 g $1,184.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Sumatriptan is a tryptamine agonist at 5-HT1B/1D receptors that is clinically used to treat migraines. Sumatriptan exhibits vasoconstrictive and gastrointestinal motility modulating activities. The anti-migraine activity of sumatriptan is likely due to its vasoconstrictive activity and ability to decrease the release of substance P and CGRP. Sumatriptan also increases gastric relaxation and delays gastric emptying. Additionally, this compound inhibits 5-HT- and capsaicin-induced signaling of transient receptor potential vanilloid (TRPV1) channels and release of CGRP in vitro and in vivo.

Product Info

Cas No.

103628-48-4

Purity

≥99%

Formula

C14H21N3O2S • C4H6O4

Formula Wt.

413.49

Chemical Name

3-[2-(Dimethyl-amin)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate; GR-43175C

IUPAC Name

butanedioic acid;1-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-N- methylmethanesulfonamide

Melting Point

165-166°C

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

S8151 MSDS PDF

Info Sheet

S8151 Info Sheet PDF

References

Blumenfeld A, Gennings C, Cady R. Pharmacological synergy: the next frontier on therapeutic advancement for migraine. Headache. 2012 Apr;52(4):636-47. PMID: 22221151.

Loyd DR, Weiss G, Henry MA, et al. Serotonin increases the functional activity of capsaicin-sensitive rat trigeminal nociceptors via peripheral serotonin receptors. Pain. 2011 Oct;152(10):2267-76. PMID: 21737202.

Muñoz-Islas E, Lozano-Cuenca J, González-Hernández A, et al. Spinal sumatriptan inhibits capsaicin-induced canine external carotid vasodilatation via 5-HT1B rather than 5-HT1D receptors. Eur J Pharmacol. 2009 Aug 1;615(1-3):133-8. PMID: 19460365.

Moro E, Crema F, De Ponti F, et al. Triptans and gastric accommodation: pharmacological and therapeutic aspects. Dig Liver Dis. 2004 Jan;36(1):85-92. PMID: 14971822.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A5225

    α-ANP (1-28), human

    Endogenous cardiomodulatory peptide; NPR-A agon...

    ≥95%
  • E4418

    β-Elemene

    Sesquiterpene found in various plant sources. <...

    ≥98%
  • A1370

    Adrenomedullin (22-52), human

    Endogenous peptide hormone, involved in cell gr...

    ≥95%
  • T3350

    Timolol Maleate

    β-adrenergic antagonist.

    ≥98%
  • L0349

    Lamotrigine

    R-type Ca2+ and voltage-gated Na+ channel block...

    ≥98%
  • C0243

    Calcitonin Gene Related Peptide (8-37), human

    Calcitonin-family peptide frgament, involved in...

    ≥95%
  • I7757

    Itopride Hydrochloride

    AChE inhibitor, D2 antagonist.

    ≥98%
  • A5282

    [Sar1 Ile8]-Angiotensin II

    Peptide, derivative of AT II, involved in vasoc...

    ≥95%
  • O4400

    Olanzapine

    AMPK activator, D1-4, 5-HT1A/2/3/6/7, M1-5 mACh...

    ≥99%
  • L283080

    LHC-165

    TLR7 agonist

    ≥99%
  • C0006

    Cabozantinib

    VEGFR2, c-Met, RET inhibitor.

    ≥98%
  • K7600

    KT5720

    PKA and PDK1 inhibitor, HCN channel blocker, po...

    ≥98%
  • C0048

    Cambinol

    SIRT inhibitor.

    ≥98%
  • H0169

    Harringtonine

    Cephalotaxine alkaloid originally found in Ceph...

    ≥98%
  • G3556

    Ginsenoside Rg3

    Triterpene saponin found in species of Panax; Î...

    ≥98%
  • S0929

    SCH-772984

    ERK1/2 inhibitor.

    ≥97%
  • G7345

    GSK-2606414

    PERK inhibitor.

    ≥99%
  • D0182

    Daunorubicin Hydrochloride

    Anthracycline, DNA intercalator; topoisomerase ...

    ≥98%
  • N1822

    Nefazodone Hydrochloride

    5-HT2 antagonist, SERT and NET inhibitor, hERG ...

    ≥98%
  • B1874

    Bestatin Hydrochloride

    Dipeptide; aminopeptidase (N/CD13) inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only