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alpha-Galactosylceramide

alpha-Galactosylceramide

Product ID G0244
Cas No. 158021-47-7
Purity ≥96%
Product Unit SizeCostQuantityStock
250 µg $224.40 In stock
1 mg $543.40 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

α-Galactosylceramide is a synthetic glycolipid found in Agelas mauritanius and other marine sponges. α-Galactosylceramide exhibits immunostimulatory activity, binding CD1d on antigen-presenting cells such as NK cells. This compound is also used to tag or stain immune cells in research models.

Product Info

Cas No.

158021-47-7

Purity

≥96%

Formula

C50H99NO9

Formula Wt.

858.34

Chemical Name

N-[(2S,3S,4R)-1-(α-D-Galactopyranosyloxy)-3,4-dihydroxy-2-octadecanyl]hexacosanamide

IUPAC Name

N-[(2S,3S,4R)-1-(α-D-Galactopyranosyloxy)-3,4-dihydroxy-2-octadecanyl]hexacosanamide

Synonym

alpha-Gal-Cer, KRN7000

Solubility

Soluble in pyridine. Solubilization in Tween20 or PBS for cell culture use see online protocol.

Appearance

Off-white solid.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Blue Ice

Downloads

MSDS

G0244 MSDS PDF

Info Sheet

G0244 Info Sheet PDF

Solubilization Protocol

G0244 Solubilization

References

Zhang F, Zhu Z, Meadows GG, et al. Chronic alcohol consumption inhibits melanoma growth but decreases the survival of mice immunized with tumor cell lysate and boosted with α-galactosylceramide. Int Immunopharmacol. 2015 Sep;28(1):359-68. PMID: 26118634.

Macho-Fernandez E, Brigl M. The Extended Family of CD1d-Restricted NKT Cells: Sifting through a Mixed Bag of TCRs, Antigens, and Functions. Front Immunol. 2015 Jul 28;6:362. PMID: 26284062.

Franck RW. C-Galactosylceramide: Synthesis and Immunology. C R Chim. 2012 Jan 1;15(1):46-56. PMID: 22408579.

Custom Order

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