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Phenylbutazone

Product ID P2810
Cas No. 50-33-9
Purity ≥98%
Product Unit SizeCostQuantityStock
25 g $56.50 In stock
100 g $149.90 In stock
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  • Product Info
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  • Description
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Description

Phenylbutazone is a non-steroidal anti-inflammatory drug (NSAID) that inhibits COX-1 and COX-2 activity; it is no longer used in humans, but was previously used to treat inflammatory diseases such as arthritis and gout. Phenylbutazone exhibits anti-inflammatory, analgesic, antipyretic, and antioxidative activities. In vivo, phenylbutazone decreases edema; in separate cellular models, it inhibits activity of myeloperoxidase.

Product Info

Cas No.

50-33-9

Purity

≥98%

Formula

C19H20N2O2

Formula Wt.

308.37

Chemical Name

4-Butyl-1,2-diphenyl-3,5-pyrazolidinedione

IUPAC Name

4-butyl-1,2-diphenylpyrazolidine-3,5-dione

Synonym

Ambene, Artrizin, Butadion, Butoz, Equipalazone, Fenibutol, Intrabutazone, Phenyzene, Tevcodyne, Uzone

Melting Point

105°C

Solubility

Soluble in water.

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

P2810 MSDS PDF

Info Sheet

P2810 Info Sheet PDF

References

Cusan C, Altinier G, Sosa S, et al. Anti-inflammatory and anti-oxidant activity of a new class of phenyl-pyrazolone derivatives. Curr Drug Discov Technol. 2006 Mar;3(1):67-73. PMID: 16712464.

Kettle AJ, Winterbourn CC. Mechanism of inhibition of myeloperoxidase by anti-inflammatory drugs. Biochem Pharmacol. 1991 May 15;41(10):1485-92. PMID: 1850278.

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