• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Hypothemycin

Hypothemycin

Product ID H9862
Cas No. 76958-67-3
Purity ≥96%
Product Unit SizeCostQuantityStock
1 mg $312.50 In stock
5 mg $1,088.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Hypothemycin is a polyketide found in Setophoma that exhibits anticancer, antifungal, and anti-parasitic activities. Hypothemycin is a resorcyclic acid lactone. This compound inhibits cell survival in melanoma and colon cancer cells. Hypothemycin also disrupts cell wall and endomembrane function in species of Pernophythora and suppresses growth of Trypanosoma in vitro and in vivo.

Product Info

Cas No.

76958-67-3

Purity

≥96%

Formula

C19H22O8

Formula Wt.

378.37

IUPAC Name

(1aR,8S,10Z,13S,14S,15aR)-5,13,14-Trihydroxy-3-methoxy-8-methyl-8,9,13,14,15,15a-hexahydro-6H-oxireno[k][2]benzoxacyclotetradecine-6,12(1aH)-dione

Solubility

DMSO: soluble acetone: soluble water: insoluble

Appearance

White to off white powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

H9862 MSDS PDF

Info Sheet

H9862 Info Sheet PDF

References

El-Elimat T, Figueroa M, Raja HA, et al. Biosynthetically Distinct Cytotoxic Polyketides from Setophoma terrestris. European J Org Chem. 2015 Jan 1;2015(1):109-121. PMID: 25574154.

Xu L, Xue J, Wu P, et al. Antifungal activity of hypothemycin against Peronophythora litchii in vitro and in vivo. J Agric Food Chem. 2013 Oct 23;61(42):10091-5. PMID: 24106914.

Nishino M, Choy JW, Gushwa NN, et al. Hypothemycin, a fungal natural product, identifies therapeutic targets in Trypanosoma brucei [corrected]. Elife. 2013 Jul 9;2:e00712. PMID: 23853713.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C0150

    Camptothecin

    Quinolone alkaloid precursor of irinotecan, ori...

    ≥98%
  • M3453

    Minoxidil

    NO donor; AR antagonist.

    ≥98%
  • A0102

    A23187 Ca-Mg

    Ca2+ ionophore.

    ≥98%, TLC
  • A5070

    Angiotensin Acetate

    Peptide, derivative of AT I, cleavage product o...

    ≥95%
  • C2956

    Cholecalciferol

    Endogenous vitamin D prodrug.

    ≥98%
  • C0375

    Ac-DEVD-pNA

    Caspase 3 substrate.

    ≥95%
  • T2833

    1-Thio-β-D-glucose Tetraacetate

    Imaging agent; Maillard reaction inhibitor.

    ≥98%
  • C0145

    Calcitriol

    Active form of vitamin D, regulates dietary Ca2...

    ≥97%
  • B3200

    BI-2536

    PLK1 inhibitor.

    ≥98%
  • T6930

    Triclosan Methyl Ether

    Diarylether; bacterial ENR binder, fatty acid s...

    ≥99%
  • E4418

    β-Elemene

    Sesquiterpene found in various plant sources. <...

    ≥98%
  • A985134

    AZD-9291

    EGFR inhibitor.

    ≥99%
  • S824766

    Sutezolid

    Bactericidal.

    ≥98%
  • P0006

    Pituitary Adenylate Cyclase-activating Polypeptide (1-38), human, sheep, rat

    Endogenous peptide, involved in paracrine and a...

    ≥95%
  • G7444

    GSK-1070916

    AurKB/C inhibitor.

    ≥98%
  • C0260

    Capsanthin

    Carotenoid originally found in Capsicum. Color ...

    Color value:100
  • T1778

    2,3,5,6-Tetramethylpyrazine

    Dihydropyrazine found in Ligusticum walliichi. ...

    ≥98%
  • A7332

    Asiatic Acid, 95%

    Triterpene aglycone originally found in Centell...

    ≥95%
  • P7318

    Pseudoginsenoside F11

    Saponin found in species of Panax; PPARγ agoni...

    ≥98%
  • D1994

    Dexrazoxane

    Iron chelator.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only