• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Indomethacin

Indomethacin

Product ID I5315
Cas No. 53-86-1
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $55.30 In stock
10 g $101.90 In stock
25 g $181.50 In stock
100 g $405.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Indomethacin is a non-steroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic, antipyretic, tocolytic, and anti-metastatic activities. Indomethacin is a non-selective COX-1 and COX-2 inhibitor that is clinically used to treat headaches; like other NSAIDs, indomethacin may induce intestinal damage or gastric lesions. Indomethacin delays premature labor in clinical settings by decreasing uterine contractility. In vitro, indomethacin decreases cancer cell migration by suppressing Ca2+ influx.

Product Info

Cas No.

53-86-1

Purity

≥98%

Formula

C19H16ClNO4

Formula Wt.

357.79

Chemical Name

1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole- 3-acetic acid

IUPAC Name

2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid

Synonym

Amuno, Idomethine.

Melting Point

158-162°C

Solubility

Insoluble in water. Soluble in ethanol (20 mg/mL), or acetone.

Appearance

White/Yellow Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

I5315 MSDS PDF

Info Sheet

I5315 Info Sheet PDF

References

Adewoye EO, Salami AT. Anti-ulcerogenic mechanism of magnesium in indomethacin induced gastric ulcer in rats. Niger J Physiol Sci. 2013 Dec 20;28(2):193-9. PMID: 24937396.

Guo YC, Chang CM, Hsu WL, et al. Indomethacin inhibits cancer cell migration via attenuation of cellular calcium mobilization. Molecules. 2013 Jun 4;18(6):6584-96. PMID: 23736792.

Summ O, Evers S. Mechanism of action of indomethacin in indomethacin-responsive headaches. Curr Pain Headache Rep. 2013 Apr;17(4):327. PMID: 23423598.

Giles W, Bisits A. Preterm labour. The present and future of tocolysis. Best Pract Res Clin Obstet Gynaecol. 2007 Oct;21(5):857-68. PMID: 17459777.

Li W, Li J, Ashok M, et al. A cardiovascular drug rescues mice from lethal sepsis by selectively attentuating a late-acting proinflammatory mediator, high mobility group box 1. J Immunol. 2007 Mar 15;178(6):3856-3864. PMID: 17339485.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • P298576

    Phomopsin A

    Cyclic hexapeptide isolated from Phomopsis lept...

    ≥98%
  • D3357

    Diosmin

    Flavone found in Teucrium.

    ≥95%
  • T5720

    Tofacitinib Citrate

    JAK1/2/3 inhibitor.

    ≥99%
  • L8248

    Lumiracoxib

    NSAID; COX-2 inhibitor.

    ≥98%
  • C0267

    Carnosol

    Diterpene compound originally found in Rosmarin...

    ≥98%
  • T165133

    Tedizolid Phosphate

    Effective against gram-positive pathogens

    ≥98%
  • F3473

    Fisetin

    Flavonoid found in various plant sources; matri...

    ≥97%
  • Z2268

    Z-FR-AMC

    Protease substrate.

    ≥95%
  • D3202

    Diallyl Trisulfide

    Organosulfur found in garlic.

    ≥98%
  • G4598

    Glycyrrhizic Acid Ammonium Hydrate

    Triterpene glycoside found in Glycyrrhiza; 11β...

    ≥93%
  • D022705

    Darunavir

    HIV and AIDS

    ≥99%
  • A4544

    Allyl Disulfide

    Organosulfur found in garlic.

    ≥98%
  • E5220

    Enfuvirtide (T-20)

    Synthetic peptide derived from HIV-1; viral fus...

    ≥95%
  • K7600

    KT5720

    PKA and PDK1 inhibitor, HCN channel blocker, po...

    ≥98%
  • I5203

    Inauhzin

    p53 activator, IMPDH and SIRT1 inhibitor.

    ≥98%
  • T0152

    Tandutinib

    FLT3, PDGFR, c-Kit inhibitor.

    ≥98%
  • M4102

    MK-1775

    Wee1 inhibitor.

    ≥98%
  • V0146

    Valsartan

    AT1 inhibitor.

    ≥98%
  • S8013

    [Tyr8]-Substance P

    Endogenous tachykinin peptide, involved in infl...

    ≥95%
  • A7460

    Asparaginase

    Catalyzes hydrolysis of asparagine.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only