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DpC

Product ID D604080
Cas No. 1382469-39-7
Purity ≥99%
Product Unit SizeCostQuantityStock
5 mg $135.00 In stock
25 mg $395.00 In stock
100 mg $985.00 In stock
Bulk Quote

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  • Description
  • Product Info
  • Shipping and Storage
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  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Dpc (Di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone) is a noval highly selective anti-tumor and anti-metastatic compound. It is highly effective against neuroblastoma cells.

Product Info

Cas No.

1382469-39-7

Purity

≥99%

Formula

C19H23N5S

Formula Wt.

353.5

Chemical Name

Di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone

IUPAC Name

1-cyclohexyl-3-(dipyridin-2-ylmethylideneamino)-1-methylthiourea

Synonym

N-Cyclohexyl-2-(di(pyridin-2-yl)methylene)-N-methylhydrazinecarbothioamide; DP4cych4mt; CHEMBL2203744; 6068Z4Y7QI

Solubility

Insoluble in water. DMSO (~5 mg/mL).

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

D604080 Info Sheet PDF

References

Sestak, V, Stariat, J1, Cermanova, J1, et al. Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents. Oncotarget. 2015; 6: 42411-42428. Retrieved from https://www.oncotarget.com/article/6389/text/

Guo, Z., Richardson, DR, Kalinowski, D. The novel thiosemicarbazone, di-2- pyridylketone 4-cyclohexyl-4-methyl-3- thiosemicarbazone (DpC), inhibits neuroblastoma growth in vitro and
in vivo via multiple mechanisms. J Hemology & Oncology (2016) 9:98

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