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B-type Natriuretic Peptide (1-32), human

B-type Natriuretic Peptide (1-32), human

Product ID B5561
Cas No. 114471-18-0
Purity ≥97%
Product Unit SizeCostQuantityStock
0.5 mg $313.40 In stock
1 mg $531.50 In stock
2.5 mg $940.30 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
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Description

Brain natriuretic peptide (BNP) binds the natriuretic peptide receptor type B (NPR-B) to exert cardiomodulatory activity. BNP is secreted by the heart; it displays lipolytic effects, contributing to fatty acid mobilization in congestive heart failure. High levels of BNP are predictive of cardiovascular problems such as heart failure and stroke. BNP also inhibits de novo collagen synthesis, increasing expression of matrix metalloproteinases 1, 2, and 3 in vitro.

Product Info

Cas No.

114471-18-0

Purity

≥97%

Formula

C143H244N50O42S4

Formula Wt.

3464.1

Synonym

Brain natriuretic peptide, BNP, Nesiritide

Solubility

Soluble in water, acid.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

B5561 MSDS PDF

Info Sheet

B5561 Info Sheet PDF

References

García-Berrocoso T, Giralt D, Bustamante A, et al. B-type natriuretic peptides and mortality after stroke: a systematic review and meta-analysis. Neurology. 2013 Dec 3;81(23):1976-85. PMID: 24186915.

Polak J, Kotrc M, Wedellova Z, et al. Lipolytic effects of B-type natriuretic peptide 1-32 in adipose tissue of heart failure patients compared with healthy controls. J Am Coll Cardiol. 2011 Sep 6;58(11):1119-25. PMID: 21884948.

Tsuruda T, Boerrigter G, Huntley BK, et al. Brain natriuretic Peptide is produced in cardiac fibroblasts and induces matrix metalloproteinases. Circ Res. 2002 Dec 13;91(12):1127-34. PMID: 12480813.

Custom Order

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