• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Diclofenac Impurity C

Diclofenac Impurity C

Product ID D324090
Cas No. 27204-57-5
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $127.20 In stock
25 mg $389.40 In stock
100 mg $1,168.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Diclofenac Impurity C (Diclofenac EP impurity C) is an impurity of Diclofenac.

Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that is clinically used to treat inflammation associated with arthritis and gout as well as other pain or inflammatory disorders; it is somewhat selective in inhibiting COX-2 over COX-1. Diclofenac exhibits anti-inflammatory, antipyretic, analgesic, antinociceptive, anticonvulsant, anti-angiogenic, anticancer chemotherapeutic, and chemopreventive activities. In vitro, the anticonvulsant/antiepileptic activity of diclofenac may stem from inhibition of delayed rectifier K+ channel amplitude and acceleration of channel inactivation; it also increases the amplitude of M-type K+ channels. This compound inhibits DMH-induced colon carcinogenesis in vivo, decreasing levels of COX-2, VEGF, and MCP-1. Diclofenac also decreases the epithelial-to-mesenchymal transition (EMT), suppressing squamous cell carcinoma tumor growth.

Product Info

Cas No.

27204-57-5

Purity

≥98%

Formula

C13H11Cl2NO

Formula Wt.

268.14

Chemical Name

[2-[(2,6-Dichlorophenyl)amino]phenyl]methanol

IUPAC Name

[2-(2,6-dichloroanilino)phenyl]methanol

Synonym

Diclofenac EP impurity C; Diclofenac impurity 3; 2-[(2,6-Dichlorophenyl)amino]benzenemethanol; o-(2,6-Dichloroanilino)benzyl Alcohol ;Diclofenac Alcohol.

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

D324090 MSDS PDF

Info Sheet

D324090 Info Sheet PDF

References

Arumugam A, Weng Z, Talwelkar SS, et al. Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by targeting Akt-ERK axis. PLoS One. 2013 Nov 8;8(11):e80076. PMID: 24260338.

Akbari E, Mirzaei E, Shahabi Majd N. Long-term Morphine-treated Rats are more Sensitive to Antinociceptive Effect of Diclofenac than the Morphine-naive rats. Iran J Pharm Res. 2013 Winter;12(1):175-84. PMID: 24250586.

Huang CW, Hung TY, Liao YK, et al. Underlying mechanism of regulatory actions of diclofenac, a nonsteroidal anti-inflammatory agent, on neuronal potassium channels and firing: an experimental and theoretical study. J Physiol Pharmacol. 2013 Jun;64(3):269-80. PMID: 23959723.

Kaur J, Sanyal SN. Diclofenac, a selective COX-2 inhibitor, inhibits DMH-induced colon tumorigenesis through suppression of MCP-1, MIP-1α and VEGF. Mol Carcinog. 2011 Sep;50(9):707-18. PMID: 21268133.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • E6231

    (−)-Epicatechin

    Flavanol originally found in Camilla (green tea...

    ≥93%
  • M1778

    S-(+)-α−Methylbenzyl Isothiocyanate

    ITC, used as chiral agent.

    ≥98%
  • B3272

    Bis(3,5-dibromosalicyl) Fumarate

    Aspirin analog; hemoglobin chain cross-linker.<...

    ≥91%
  • C2942

    Mechlorethamine Hydrochloride

    Nitrogen mustard, DNA alkylator.

    ≥98%
  • H9712

    (E)-4-Hydroxytamoxifen

    SERM.

    ≥97%
  • L0400

    LB-100

    PP2A inhibitor.

    ≥98%
  • C7997

    C-Type Natriuretic Peptide (1-22), human

    Endogenous cardiomodulatory peptide; NPR-B agon...

    ≥95%
  • I7360

    Isosorbide Mononitrate

    NO donor.

    ≥98%
  • A1331

    Adipokinetic Hormone, locust

    Neuropeptide hormone found in insects, involved...

    ≥95%
  • N6076

    N(p-Tosyl)-GPR-pNA

    Thrombin substrate used to measure thrombin act...

    ≥95%
  • N1980

    Neuromedin B, pig

    Endogenous bombesin-related peptide, involved i...

    ≥95%
  • D3228

    Dihydromyristicin

    Found in parsley.

    ≥98%
  • T5769

    Toremifene Base

    SERM, androgen modulator.

    ≥98%
  • D3300

    (Z)-1,-Bis(2-methoxy-5-(trifluoromethyl)phenyl)diazene oxide

    Azoxy compound

    ≥98%
  • G720009

    GS-9901

    Selective inhibitor of the delta isoform of PI3...

    ≥99%
  • C1620

    Ceftiofur Hydrochloride

    β-lactam; penicillin binding protein inhibitor...

    ≥90%
  • M5675

    Motilin, canine

    Endogenous peptide hormone; motilin agonist.

    ≥95%
  • R5602

    Ro 20-1724

    Phosphodiesterase inhibitor that produces anti-...

    ≥98%
  • B3300

    BI-6727

    PLK1 inhibitor.

    ≥99%
  • Z7477

    ZSTK474

    PI3K inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only