• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Isoflurane

Isoflurane

Product ID I7258
Cas No. 26675-46-7
Purity ≥98%
Product Unit SizeCostQuantityStock
250 mg $58.50 In stock
1 g $84.30 In stock
5 g $110.40 In stock
25 g $162.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Isoflurane is an anesthetic most commonly used in veterinary medicine. Isoflurane exhibits cardiomodulatory, neuromodulatory, and pro-inflammatory activities. In diabetic rats, isofluorane decreases cardiac force and intracellular Ca2+ amplitude. Isoflurane also increases IL-6 and NF-κB levels in glioma cells and microglia. In other cellular models, isoflurane inhibits L-type voltage-gated Ca2+ channel currents at resting membrane potential. Additionally, isofluorane binds and modulates signaling by ATP synthase and NADH dehydrogenase. Isoflurane also inhibits delayed rectifier and A-type K+ channels and NMDA receptors, activates Ca2+ ATPase and ATP-sensitive K+ channels, and potentiates GABA-A and glycine (GlyR) receptors.

Product Info

Cas No.

26675-46-7

Purity

≥98%

Formula

C3H2ClF5O

Formula Wt.

184.49

Chemical Name

2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane

IUPAC Name

2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane

Synonym

1-Chloro-2,2,2-trifluoroethyl difluoromethyl ether; Forane; 2-Chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane

Solubility

Soluble in water (4.47 mg/ml at 37 °C), and organic liquids including fats and oils

Appearance

Clear and Colorless mobile heavy liquid

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

I7258 MSDS PDF

Info Sheet

I7258 Info Sheet PDF

References

Shen X, Bhatt N, Xu J, et al. Effect of isoflurane on myocardial energetic and oxidative stress in cardiac muscle from zucker diabetic Fatty rat. J Pharmacol Exp Ther. 2014 Apr;349(1):21-8. PMID: 24431470.

Fanchaouy M, Cubano L, Maldonado H, et al. PKC independent inhibition of voltage gated calcium channels by volatile anesthetics in freshly isolated vascular myocytes from the aorta. Cell Calcium. 2013 Oct;54(4):257-65. PMID: 23948226.

Zhang L, Zhang J, Yang L, et al. Isoflurane and sevoflurane increase interleukin-6 levels through the nuclear factor-kappa B pathway in neuroglioma cells. Br J Anaesth. 2013 Jun;110 Suppl 1:i82-91. PMID: 23604542.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A7208

    Ascomycin

    FK506 analog; calcineurin inhibitor.

    ≥98%
  • D3448

    Dimethyl Fumarate

    Fumaric acid methyl ester; nAChR agonist, indir...

    ≥98%
  • C002045

    Oxazolidine Cabazitaxel

    Synthesis impurity

    ≥95%
  • A0902

    N-Acetyl-S-(N′-phenylhexylthiocarbamoyl)-L-cysteine

    Cysteine-ITC conjugate, antioxidant; HDAC inhib...

    ≥98%
  • I0416

    Iberin

    Isothiocyanate found in cruciferous vegetables,...

    ≥97%
  • F5870

    N-formyl-Met-Leu-Phe

    Peptide, involved in neutrophil activation; FPR...

    ≥95%
  • B1879

    Betamethasone Valerate

    Synthetic steroid hormone; glucocorticoid agoni...

    ≥98%
  • F3473

    Fisetin

    Flavonoid found in various plant sources; matri...

    ≥97%
  • G8850

    GW-5074

    c-Raf inhibitor.

    ≥98%
  • G7440

    GSK-1120212

    MEK1/2 inhibitor.

    ≥98%
  • T0249

    Tamibarotene

    RARα/β agonist.

    ≥98%
  • C0375

    Ac-DEVD-pNA

    Caspase 3 substrate.

    ≥95%
  • G124084

    GDC-0973

    MEK1 inhibitor.

    ≥99%
  • M3576

    Mitotane

    Diphenylmethane, inhibits secretion of cortisol...

    ≥98%
  • R3206

    Riboflavin

    Essential vitamin (B2) found in vegetables, dai...

    ≥97%
  • W7200

    WS3

    Islet β cell proliferation stimulator.

    ≥98%
  • P6854

    Progesterone

    Endogenous steroid hormone involved in reproduc...

    ≥98%
  • G0048

    γ-Amino Butyric Acid

    Endogenous neurotransmitter; GABA agonist.

    ≥99%
  • B4402

    Blasticidin S Hydrochloride

    Protein translation inhibitor.

    ≥98%
  • G3558

    20R-Ginsenoside Rh2

    Triterpene saponin found in Panax.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only