Indomethacin

Name: Indomethacin
SKU: I5315
Availability: InStock

Product ID I5315

Cas No. 53-86-1

Purity ≥98%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Indomethacin is a non-steroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic, antipyretic, tocolytic, and anti-metastatic activities. Indomethacin is a non-selective COX-1 and COX-2 inhibitor that is clinically used to treat headaches; like other NSAIDs, indomethacin may induce intestinal damage or gastric lesions. Indomethacin delays premature labor in clinical settings by decreasing uterine contractility. In vitro, indomethacin decreases cancer cell migration by suppressing Ca2+ influx.

Product Info

Cas No.	53-86-1
Purity	≥98%
Formula	C₁₉H₁₆ClNO₄
Formula Wt.	357.79
Chemical Name	1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole- 3-acetic acid
IUPAC Name	2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
Synonym	Amuno, Idomethine.
Melting Point	158-162°C
Solubility	Insoluble in water. Soluble in ethanol (20 mg/mL), or acetone.
Appearance	White/Yellow Crystalline Powder

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	I5315 MSDS PDF
Info Sheet	I5315 Info Sheet PDF

References

Adewoye EO, Salami AT. Anti-ulcerogenic mechanism of magnesium in indomethacin induced gastric ulcer in rats. Niger J Physiol Sci. 2013 Dec 20;28(2):193-9. PMID: 24937396.

Guo YC, Chang CM, Hsu WL, et al. Indomethacin inhibits cancer cell migration via attenuation of cellular calcium mobilization. Molecules. 2013 Jun 4;18(6):6584-96. PMID: 23736792.

Summ O, Evers S. Mechanism of action of indomethacin in indomethacin-responsive headaches. Curr Pain Headache Rep. 2013 Apr;17(4):327. PMID: 23423598.

Giles W, Bisits A. Preterm labour. The present and future of tocolysis. Best Pract Res Clin Obstet Gynaecol. 2007 Oct;21(5):857-68. PMID: 17459777.

Li W, Li J, Ashok M, et al. A cardiovascular drug rescues mice from lethal sepsis by selectively attentuating a late-acting proinflammatory mediator, high mobility group box 1. J Immunol. 2007 Mar 15;178(6):3856-3864. PMID: 17339485.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Name
This field is for validation purposes and should be left unchanged.

Indomethacin

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

LY-2874455

Latrunculin B

GSK-2830371

Streptozocin

Cycloastragenol

AG-1478

Alytesin

Hemorphin-7

Ellagic Acid

Triamcinolone Acetonide

Pravastatin Sodium

Mevinolin

Snake venom – Bothrops alternatus (urutu)

Ofloxacin

Metformin Hydrochloride

β-Cembrenediol Methyl Ether

(R)-Synephrine

Canrenone

Quinacrine Dihydrochloride Dihydrate

Nomilin

Footer