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γ-Neuropeptide, rabbit

γ-Neuropeptide, rabbit

Product ID N1988
Cas No. 114882-65-4
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $115.50 Please Inquire
1 mg $194.30 Please Inquire
2.5 mg $378.00 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

γ-Neuropeptide is an endogenous tachykinin/neurokinin peptide that binds neurokinin (NK) receptors, displaying some selectivity for NK2 isoforms. This peptide mediates hypothalamic-pituitary-adrenal (HPA) axis signaling and reproductive hormone release, inhibiting hypothalamic secretion of luteinizing hormone (LH). Additionally, γ-neuropeptide induces vasodilation and hypotensive activity in vivo. γ-Neuropeptide may play a role in gastrointestinal motility, as it stimulates smooth muscle contraction in the gastrointestinal tract; it also stimulates smooth muscle contraction in the respiratory tract. γ-Neuropeptide forms complexes with Cu(II) as well.

Product Info

Cas No.

114882-65-4

Purity

≥95%

Formula

C99H158N34O29S

Formula Wt.

2320.64

Synonym

gamma-neuropeptide

Solubility

Soluble in water.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

N1988 Info Sheet PDF

References

Pietruszka M, Jankowska E, Kowalik-Jankowska T, et al. Complexation abilities of neuropeptide gamma toward copper(II) ions and products of metal-catalyzed oxidation. Inorg Chem. 2011 Aug 15;50(16):7489-99. PMID: 21770367.

Kim EJ, Kim CH, Seo JK, et al. Structure-activity relationship of neuropeptide gamma derived from mammalian and fish. J Pept Res. 2005 Dec;66(6):395-403. PMID: 16316456.

Debeljuk L, Lasaga M. Modulation of the hypothalamo-pituitary-gonadal axis and the pineal gland by neurokinin A, neuropeptide K and neuropeptide gamma. Peptides. 1999;20(2):285-99. PMID: 10422885.

Yuan L, Burcher E, Nail BS. Characterization of tachykinin receptors mediating bronchomotor and vasodepressor responses to neuropeptide gamma and substance P in the anaesthetized rabbit. Pulm Pharmacol Ther. 1998 Feb;11(1):31-9. PMID: 9802961.

Custom Order

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