• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
2-Deoxy-D-glucose

2-Deoxy-D-glucose

Product ID D1859
Cas No. 154-17-6
Purity ≥99%
Product Unit SizeCostQuantityStock
1 g $97.70 In stock
5 g $329.70 In stock
25 g $1,365.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

2-deoxy-D-glucose inhibits glucose metabolism and is used as a biomarker of glucose metabolism, hypoxia, and angiogenesis in a variety of models and cell types, including neurotoxicity, cancer, and autoimmune disease; the 2-OH group of glucose is replaced by a hydrogen and therefore this compound can not be metabolized properly. 2-deoxy-D-glucose inhibits N-linked glycosylation and glycolysis, inhibiting surface expression of MICA/B and other NKG2D ligands on cells. This compound also exhibits anticancer and pro-oxidative activities, increasing oxidative stress and mimicking glucose deprivation, resulting in cell death of cancer cells.

Product Info

Cas No.

154-17-6

Purity

≥99%

Formula

C6H12O5

Formula Wt.

164.16

IUPAC Name

(2S,4S,5S,6S)-6-(hydroxymethyl)oxane-2,4,5-triol

Melting Point

146-147°C

Appearance

White to slight yellow powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

D1859 MSDS PDF

Info Sheet

D1859 Info Sheet PDF

References

Kaira K, Murakami H, Endo M, et al. Biological correlation of (18)F-FDG uptake on PET in pulmonary neuroendocrine tumors. Anticancer Res. 2013 Oct;33(10):4219-28. PMID: 24122985.

Andresen L, Skovbakke SL, Persson G, et al. 2-deoxy D-glucose prevents cell surface expression of NKG2D ligands through inhibition of N-linked glycosylation. J Immunol. 2012 Feb 15;188(4):1847-55. PMID: 22227571.

Shutt DC, O'Dorisio MS, Aykin-Burns N, et al. 2-deoxy-D-glucose induces oxidative stress and cell killing in human neuroblastoma cells. Cancer Biol Ther. 2010 Jun 1;9(11):853-61. PMID: 20364116.

Nowak M, Carrasquillo JA, Yarboro CH, et al. A pilot study of the use of 2-[18F]-fluoro-2-deoxy-D-glucose-positron emission tomography to assess the distribution of activated lymphocytes in patients with systemic lupus erythematosus. Arthritis Rheum. 2004 Apr;50(4):1233-8. PMID: 15077306.

Böhmer R, Rommel K. The behaviour of different markers of the mucosal extracellular space in rat small intestine. Acta Hepatogastroenterol (Stuttg). 1975 Dec;22(6):398-403. PMID: 1211066.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • N0160

    NAP Peptide

    Octapeptide derived from activity-dependent neu...

    ≥95%
  • A9713

    AZD-3514

    Androgen receptor downregulator.

    ≥98%
  • M1566

    (+)-S-Methyl-L-cysteine-S-oxide

    Alliin analog found in cruciferous vegetables.<...

    ≥98%
  • M3321

    Mifepristone

    Synthetic steroid, contraceptive; PR and glucoc...

    ≥98%
  • T5769

    Toremifene Base

    SERM, androgen modulator.

    ≥98%
  • E846184

    Everolimus EP Impurity B

    Everolimus impurity

    ≥96% (mix of E/Z)
  • C9779

    Cytisine

    Alkaloid found in Fabaceae family plants; α3β...

    ≥98%
  • P0256

    Pantoprazole Sodium Sesquihydrate

    H+/K+ ATPase and ROCK-2 inhibitor.

    ≥98%
  • P0010

    Pituitary Adenylate Cyclase-activating Polypeptide-related Peptide, human

    Peptide, involved in paracrine and autocrine ce...

    ≥95%
  • B1996

    BEZ235

    PI3K and mTOR inhibitor.

    ≥98%
  • K9858

    Kyotorphin

    Opioid neuropeptide; kyotorphin agonist.

    ≥95%
  • K0030

    Kahweol

    Diterpene found in coffee beans.

    ≥97%
  • A6058

    Apoptosis Activator 2

    Apoptosis inducing agent.

    ≥98%
  • U6857

    Urodilatin CCC

    ANP fragment, natriuretic peptide; Na+/K+ ATPas...

    ≥98%
  • H0207

    Hepatitis B Virus Core Protein (128-140)

    B cell epitope found on hepatitis B viral core ...

    ≥95%
  • F5773

    Fosinopril Sodium

    ACE inhibitor.

    ≥98%
  • G4598

    Glycyrrhizic Acid Ammonium Hydrate

    Triterpene glycoside found in Glycyrrhiza; 11β...

    ≥93%
  • X0254

    Xanthohumol

    Prenylated flavonoid found in Humulus lupulus.<...

    ≥98%
  • A0977

    Actinomycin

    Polypeptide antibiotic produced from Streptomyc...

    ≥98%
  • G3554

    Ginsenoside Rb3

    Triterpene saponin found in species of Panax.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only