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Glucagon-like Peptide I Amide (7-36), human

Glucagon-like Peptide I Amide (7-36), human

Product ID G4481
Cas No. 107444-51-9
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $310.80 In stock
1 mg $527.40 In stock
2.5 mg $932.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Glucagon-like peptide 1 (GLP-1) is an endogenous peptide hormone that binds GLP-1 receptors, increasing cAMP and insulin secretion. GLP-1 primarily exhibits anorexigenic, anti-diabetic, and gastrointestinal modulatory activities. GLP-1 decreases food intake and glucagon levels in animal models and also slows gastric emptying. In subjects with type 2 diabetes, the response of GLP-1 to glucose is impaired and subjects show abnormally low levels of GLPs.

Product Info

Cas No.

107444-51-9

Purity

≥95%

Formula

C149H229N40O45

Formula Wt.

3297.7

Synonym

GLP-1

Solubility

Soluble in water (1 mg/mL).

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

G4481 MSDS PDF

Info Sheet

G4481 Info Sheet PDF

References

Kim S, Wan Kim S, Bae YH. Synthesis, bioactivity and specificity of glucagon-like peptide-1 (7-37)/polymer conjugate to isolated rat islets. Biomaterials. 2005 Jun;26(17):3597-606. PMID: 15621250.

Vahl TP, Paty BW, Fuller BD, et al. Effects of GLP-1-(7-36)NH2, GLP-1-(7-37), and GLP-1- (9-36)NH2 on intravenous glucose tolerance and glucose-induced insulin secretion in healthy humans. J Clin Endocrinol Metab. 2003 Apr;88(4):1772-9. PMID: 12679472.

Mannucci E, Ognibene A, Cremasco F, et al. Glucagon-like peptide (GLP)-1 and leptin concentrations in obese patients with Type 2 diabetes mellitus. Diabet Med. 2000 Oct;17(10):713-9. PMID: 11110504.

Nauck MA. Glucagon-like peptide 1 (GLP-1): a potent gut hormone with a possible therapeutic perspective. Acta Diabetol. 1998 Oct;35(3):117-29. PMID: 9840447.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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