• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Indolicidin

Indolicidin

Product ID I5215
Cas No. 140896-21-5
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $126.00 In stock
1 mg $207.90 In stock
2.5 mg $336.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Indolicidin is an antimicrobial peptide (AMP) that interacts with and disrupts membranes. Indolicidin binds negatively charged lipid membranes and induces release of vesicle contents but does not form pores like other AMPs. Indolicidin exhibits antibacterial, hemolytic, and anti-inflammatory activities. This peptide displays antibiotic activity against both gram positive and gram negative bacteria, inhibiting growth of Acinetobacter, Staphyloccocus, and Nocardia, among others. Additionally, indolicidin inhibits production of NO and iNOS in LPS-stimulated macrophages and inhibits production of TNF-α in various other cell lines.

Product Info

Cas No.

140896-21-5

Purity

≥95%

Formula

C100H132N26O13

Formula Wt.

1906.33

Solubility

Soluble in water (1 mg/mL), DMSO.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

I5215 MSDS PDF

Info Sheet

I5215 Info Sheet PDF

References

Vila-Farres X, Garcia de la Maria C, López-Rojas R, et al. In vitro activity of several antimicrobial peptides against colistin-susceptible and colistin-resistant Acinetobacter baumannii. Clin Microbiol Infect. 2012 Apr;18(4):383-7. PMID: 21672084.

Végh AG, Nagy K, Bálint Z, et al. Effect of antimicrobial peptide-amide: indolicidin on biological membranes. J Biomed Biotechnol. 2011;2011:670589. PMID: 21765635.

Rieg S, Kaasch AJ, Wehrle J, et al. Susceptibility of clinical Staphylococcus aureus isolates to innate defense antimicrobial peptides. Microbes Infect. 2011 Aug;13(8-9):761-5. PMID: 21473929.

Rokitskaya TI, Kolodkin NI, Kotova EA, et al. Indolicidin action on membrane permeability: carrier mechanism versus pore formation. Biochim Biophys Acta. 2011 Jan;1808(1):91-7. PMID: 20851098.

Rieg S, Meier B, Fähnrich E, et al. Differential activity of innate defense antimicrobial peptides against Nocardia species. BMC Microbiol. 2010 Feb 23;10:61. PMID: 20178618.

Nan YH, Park KH, Park Y, et al. Investigating the effects of positive charge and hydrophobicity on the cell selectivity, mechanism of action and anti-inflammatory activity of a Trp-rich antimicrobial peptide indolicidin. FEMS Microbiol Lett. 2009 Mar;292(1):134-40. PMID: 19191872.

Bowdish DM, Davidson DJ, Scott MG, et al. Immunomodulatory activities of small host defense peptides. Antimicrob Agents Chemother. 2005 May;49(5):1727-32. PMID: 15855488.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • N3346

    Nilotinib

    Phenylamino pyridine; Abl, c-Kit, PDGFR, PP2A i...

    ≥99%
  • G0152

    Ganciclovir

    Nucleoside (guanosine) analog; DNA chain termin...

    ≥98%
  • A0816

    Acemetacin

    Glycolic acid ester prodrug of indomethacin, NS...

    ≥98%
  • V1600

    VE-821

    ATR inhibitor.

    ≥98%
  • B6959

    Bromosporine

    BRD2/4/9 and CECR2 inhibitor.

    ≥99%
  • R1724

    Regadenoson

    Adenosine A2A agonist.

    ≥99%
  • S800000

    SU-9516

    CDK2 inhibitor.

    ≥98%
  • L5993

    Loxoprofen Sodium Dihydrate

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • T2404

    TG101348

    JAK2 inhibitor.

    ≥98%
  • M4004

    MK-2461

    MET, FGFR, PDGFR inhibitor.

    ≥99%
  • D0025

    DAMGO

    Synthetic peptice; μOR agonist.

    ≥95%
  • F285081

    Fidaxomicin

    Macrocycle

    ≥98%
  • P3018

    Phellodendrine

    Quaternary base alkaloid found in Phellodendron...

    ≥98%
  • P698583

    Prostaglandin E2

    principal metabolic product of COX-2

    ≥98%
  • A822686

    Aureothricin

    Aureothricin is a member of the dithiolopyrrolo...

    ≥98%
  • A4853

    β-Amyloid Peptide (1-42), human

    Endogenous APP peptide cleavage product, primar...

    ≥95%
  • M324081

    Micafungin Sodium

    Echinocandin antifungal

    ≥98%
  • K7600

    KT5720

    PKA and PDK1 inhibitor, HCN channel blocker, po...

    ≥98%
  • I5414

    Indapamide

    Thiazide-like diuretic; Kv7.1 and minK K+ chann...

    ≥98%
  • C9863

    Cyproconazole

    Triazole; 14-α demethylase inhibitor, voltage-...

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only