• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Phellodendrine

Phellodendrine

Product ID P3018
Cas No. 6873-13-8
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $91.00 In stock
5 mg $364.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Phellodendrine is a quaternary base alkaloid found in the bark of Phellodendron. Phellodendrine exhibits immunosuppressive and anti-inflammatory activities. Phellodendrine inhibits local semisyngenic and allogenic graft-versus-host (GVH) reactions and suppresses the induction of delayed-type hypersensitivity reactions without affecting the overall antibody response in animal models. Additionally, phellodendrine decreases urinary protein, plasma creatine, and plasma cholesterol levels in animal models of crescentic-type antiGBM nephritis, inhibiting crescent formation, adhesion, and fibrinoid necrosis in glomeruli; this compound also prevents nephritis-induced increases in immune cells and cytokines.

Product Info

Cas No.

6873-13-8

Purity

≥98%

Formula

C20H24NO4

Formula Wt.

342.41

Chemical Name

(7S,13aS)-3,10-dimethoxy-7-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-7-ium-2,11-diol

IUPAC Name

(7S,13aS)-3,10-dimethoxy-7-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-7-ium-2,11-diol

Synonym

(7S,13aS)-3,10-dimethoxy-7-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-7-ium-2,11-diol; Phallodendrin; OB-5 Compound

Solubility

Soluble in Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone

Appearance

White to off white powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

P3018 MSDS PDF

Info Sheet

P3018 Info Sheet PDF

References

Mori H, Fuchigami M, Inoue N, et al. Principle of the bark of Phellodendron amurense to suppress the cellular immune response: effect of phellodendrine on cellular and humoral immune responses. Planta Med. 1995 Feb;61(1):45-9. PMID: 7700991.

Hattori T, Furuta K, Hayashi K, et al. Studies on the antinephritic effects of plant components (6): antinephritic effects and mechanisms of phellodendrine (OB-5) on crescentic-type anti-GBM nephritis in rats (2). Jpn J Pharmacol. 1992 Nov;60(3):187-95. PMID: 1491511.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • V344761

    Vitamin K2

    2-methyl-1,4-naphthoquinone derivative

    ≥98%
  • P1764

    Pep-1 Peptide

    Cell-penetrating peptide, carries large conjuga...

    ≥95%
  • N1984

    Neuropeptide FF

    Endogenous RF-amide peptide, involved in nocice...

    ≥95%
  • B030964

    BAY-1816032

    BUB1 inhibitor.

    ≥99%
  • G0248

    (-)-Gambogic Acid

    Xanthone found in Garcinia hanburyi.

    ≥99%
  • G0106

    Gabapentin

    GABA analog; GABA potentiator, adenosine A1 ago...

    ≥98%
  • G4581

    Glucosamine Sulfate Potassium Chloride

    Endogenous amino acid sugar involved in cartila...

    ≥98%
  • U451349

    Ulixertinib

    May induce apoptosis in lymphoma cell lines.

    ≥98%
  • S1843

    L-Selectin

    Endogenous adhesion molecule, binds PKC, calmod...

    ≥95%
  • N3276

    Nitroso(acetoxymethyl)methylamine

    NNK precursor found in tobacco smoke; carcinoge...

    ≥97%
  • G4781

    Glucoraphanin Potassium

    Glucosinolate found in cruciferous vegetables.<...

    ≥98%
  • U6901

    Uracil

    Endogenous pyrimidine base required for product...

    ≥98%
  • P1869

    Perindopril Erbumine

    ACE inhibitor.

    ≥95%
  • B1853

    1,4-Benzoquinone

    Precursor in the synthesis of hydroquinone, ant...

    ≥98%
  • M5752

    Monastrol

    Pyrimidine derivative; kinesin Eg5 inhibitor.

    ≥95%
  • T3040

    Thienylpentyl Isothiocyanate

    Thienylbutyl ITC analog.

    ≥98%
  • M1669

    6-Mercaptopurine Monohydrate

    Thiopurine antimetabolite; PRPP amidotransferas...

    ≥98%
  • G1651

    Geniposidic Acid

    Iridoid glucoside found in Eucommia, Castilleja...

    ≥98%
  • A7461

    Asperosaponin VI

    Triterpene saponin found in Dipsacus asper.

    ≥98%
  • B177550

    Benzbromarone

    Non-competitive inhibitor of xanthine oxidase.<...

    ≥99%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only