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Benzbromarone

Product ID B177550
Cas No. 3562-84-3
Purity ≥99%
Product Unit SizeCostQuantityStock
100 mg $39.70 In stock
500 mg $51.10 In stock
1 g $73.80 In stock
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Description

Benzbromarone is a non-competitive inhibitor of xanthine oxidase. It has been evaluated as an effective treatment for gout, thanks to its ability to potently inhibit CYP2C9, reducing urate reabsorption which in turn lowers serum urate levels. It has also shown antioxidant effects in rats with angiotensin-II and salt-induced hypertension, where it reduces the presence of oxidative stress markers.

Product Info

Cas No.

3562-84-3

Purity

≥99%

Formula

C17H12Br2O3

Formula Wt.

424.09

Chemical Name

(3,5-dibromo-4-hydroxyphenyl)-(2-ethyl-1-benzofuran-3-yl)methanone

IUPAC Name

(3,5-dibromo-4-hydroxyphenyl)-(2-ethyl-1-benzofuran-3-yl)methanone

Synonym

Desuric, Benzbromaron, Urinorm

Solubility

Insoluble in water. Soluble in DMSO - ~40 mg/mL.

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

B177550 MSDS PDF

Info Sheet

B177550 Info Sheet PDF

References

Azevedo V., Kos I., et al. Benzbromarone in the treatment of gout. Adv Rheumatol. 59(1):37 (2019). PMID: 31391099.

Muraya N., Kadowaki D., et al. Benzbromarone Attenuates Oxidative Stress in Angiotensin II- and Salt-Induced Hypertensive Model Rats. Oxi Med Cell Longev. 2018:7635274 (2018). PMID: 29967665.

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