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Ropinirole Hydrochloride

Product ID R5661
Cas No. 91374-20-8
Purity ≥99%
Product Unit SizeCostQuantityStock
25 mg $114.30 In stock
100 mg $243.20 In stock
500 mg $1,001.80 In stock
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  • Product Info
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  • Description
  • Product Info
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Description

Ropinirole is an indoline agonist at D2/3 receptors that is clinically used to treat restless leg syndrome and Parkinson’s disease. Ropinirole prevents dopaminergic neuron damage and MPTP-induced changes in motor coordination and balance in animal models, exhibiting neuroprotective benefit. Ropinirole also displays antidepressant activity, decreasing immobility time in the forced swim test.

Product Info

Cas No.

91374-20-8

Purity

≥99%

Formula

C16H24N2O • HCl

Formula Wt.

296.84

Chemical Name

4-[2-(Dipropylamino)-ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride

IUPAC Name

4-[2-(dipropylamino)ethyl]-1,3-dihydroindol-2-one;hydrochloride

Synonym

SKF-101468A

Melting Point

241-243°C

Solubility

Soluble in water.

Appearance

Light Yellow Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

R5661 MSDS PDF

Info Sheet

R5661 Info Sheet PDF

References

Park G, Park YJ, Yang HO, et al. Ropinirole protects against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-induced neurotoxicity in mice via anti-apoptotic mechanism. Pharmacol Biochem Behav. 2013 Mar;104:163-8. PMID: 23369986.

Ferini-Strambi L. Treatment options for restless legs syndrome. Expert Opin Pharmacother. 2009 Mar;10(4):545-54. PMID: 19284359.

Dhir A, Kulkarni SK. Involvement of dopamine (DA)/serotonin (5-HT)/sigma (sigma) receptor modulation in mediating the antidepressant action of ropinirole hydrochloride, a D2/D3 dopamine receptor agonist. Brain Res Bull. 2007 Sep 14;74(1-3):58-65. PMID: 17683790.

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